Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HK1 | P19367 | 1/20 | 0.42 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10467315 | 0.84 | ALDH1A1 (0.43) | HSD17B10CYP2C19ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL10467546 | 0.77 | TRPM8 (0.45) | CYP2C19ALDH1A1SMN1; SMN2RAB9AATM | |
| SCHEMBL13193314 | 0.72 | ALDH1A1 (0.54) | HSD17B10CYP2C19ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL19846962 | 0.72 | HSD17B10 (0.60) | HSD17B10CYP2C19ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL7188506 | 0.72 | GABRA1 (0.45) | HSD17B10CYP2C19ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL10468538 | 0.72 | KDM4E (0.48) | ALDH1A1L3MBTL1HTTNPSR1LMNA | |
| SCHEMBL10465927 | 0.72 | NR4A2 (0.50) | HSD17B10ALDH1A1SMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL22070145 | 0.71 | KDM4E (0.46) | HSD17B10CYP2C19ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL12987657 | 0.70 | ALDH1A1 (0.49) | HSD17B10CYP2C19ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL6166986 | 0.69 | KMT2A (0.58) | HSD17B10ALDH1A1LMNAKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4940709-A | PLATELET ACTIVATING FACTOR | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-07-10 | — | — | US | disclosed |
| US-4806538-A | ANTICOAGULANT, HYPOTENSIVE AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-02-21 | — | — | US | disclosed |
| EP-0243122-A2 | Piperazine compound as PAF-antagonist | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-10-28 | — | — | EP | disclosed |