Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 2/20 | 0.39 |
| ▸ | GABRD | O14764 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22070145 | 0.85 | KDM4E (0.46) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL10467547 | 0.84 | HSD17B10 (0.45) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL10468538 | 0.82 | KDM4E (0.48) | ALDH1A1KDM4EHTT | |
| SCHEMBL10776104 | 0.75 | TRPM8 (0.47) | ALDH1A1CYP2C19KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL10467337 | 0.75 | TRPM8 (0.47) | ALDH1A1CYP2C19KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL10465927 | 0.75 | NR4A2 (0.50) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL9499951 | 0.74 | GPR3 (0.47) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL632069 | 0.72 | ACLY (0.48) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL27680089 | 0.72 | KDM4E (0.50) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL17616023 | 0.71 | GPR3 (0.52) | ALDH1A1MAPTKDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4940709-A | PLATELET ACTIVATING FACTOR | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-07-10 | — | — | US | disclosed |
| US-4806538-A | ANTICOAGULANT, HYPOTENSIVE AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-02-21 | — | — | US | disclosed |
| EP-0243122-A2 | Piperazine compound as PAF-antagonist | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-10-28 | — | — | EP | disclosed |