Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10425662 | 0.90 | ALDH1A1 (0.40) | ALDH1A1LMNAHSD17B10GLO1CYP2D6 | |
| SCHEMBL17984614 | 0.79 | ALDH1A1 (0.41) | ALDH1A1LMNAHSD17B10HPGDALOX15 | |
| SCHEMBL6070239 | 0.77 | ALDH1A1 (0.44) | ALDH1A1LMNAHSD17B10GLO1CYP2D6 | |
| SCHEMBL15046951 | 0.75 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10GLO1CYP2D6 | |
| SCHEMBL2307304 | 0.73 | ALDH1A1 (0.37) | ALDH1A1LMNAHSD17B10GLO1CYP2D6 | |
| SCHEMBL642855 | 0.73 | CYP2D6 (0.46) | ALDH1A1LMNAHSD17B10GLO1CYP2D6 | |
| SCHEMBL4900324 | 0.73 | MEN1 (0.49) | ALDH1A1LMNAGAAMAPTUSP2 | |
| SCHEMBL11461030 | 0.72 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10GLO1CYP2D6 | |
| SCHEMBL31208165 | 0.72 | ALDH1A1 (0.36) | ALDH1A1LMNAHSD17B10GLO1CYP2D6 | |
| SCHEMBL28116044 | 0.72 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10GLO1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160237059-A1 | HETEROCYCLIC SUBSTITUTED TRIFLUOROMETHYL PYRIMIDINONES AND THEIR USE | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-08-18 | — | — | US | disclosed |
| US-4929738-A | BACTERICIDES, FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1990-05-29 | — | — | US | disclosed |
| US-4864029-A | MICROBIOCIDE INTERMEDIATES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-09-05 | — | — | US | disclosed |
| US-4767775-A | Substituted pyrazolin-5-ones, composition containing them, and method of combating fungi or bacteria | BAYER AKTIENGESELLSCHAFT (DE) | 1988-08-30 | — | — | US | disclosed |
| US-4598147-A | THIAZOLE INTERMEDIATES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160237059-A1 | HETEROCYCLIC SUBSTITUTED TRIFLUOROMETHYL PYRIMIDINONES AND THEIR USE | REN, GLS, FIBP | ALDH1A1 1089/4885LMNA 604/4885HSD17B10 4092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.