Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | MGAT2 | Q10469 | 2/20 | 0.34 |
| ▸ | OTUD7B | Q6GQQ9 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN4A | P35499 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10519147 | 0.82 | PIM1 (0.35) | MMP2MMP9ALDH1A1LMNAPIM1 | |
| SCHEMBL10469653 | 0.76 | ALDH1A1 (0.36) | MMP2MMP9ALDH1A1LMNAPIM1 | |
| SCHEMBL10469654 | 0.76 | ALDH1A1 (0.36) | MMP2MMP9ALDH1A1LMNAPIM1 | |
| SCHEMBL7711516 | 0.75 | MMP2 (0.39) | MMP2MMP9ALDH1A1LMNAPIM1 | |
| SCHEMBL7712019 | 0.70 | ALDH1A1 (0.38) | MMP2MMP9ALDH1A1LMNAPIM1 | |
| SCHEMBL7713916 | 0.68 | LMNA (0.40) | MMP2MMP9ALDH1A1LMNAMAPT | |
| SCHEMBL7712022 | 0.68 | LMNA (0.34) | MMP2MMP9ALDH1A1LMNAPIM1 | |
| SCHEMBL7711504 | 0.67 | MMP2 (0.39) | MMP2MMP9ALDH1A1LMNAMGAT2 | |
| SCHEMBL7708682 | 0.66 | MMP2 (0.36) | MMP2MMP9ALDH1A1LMNAGAA | |
| SCHEMBL7711670 | 0.65 | LMNA (0.35) | MMP2MMP9ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4958022-A | Polycyclic compounds | BASF AKTIENGESELLSCHAFT (DE) | 1990-09-18 | — | — | US | disclosed |
| EP-0330131-A1 | Polycyclic compounds and their use | BASF Aktiengesellschaft (DE) | 1989-08-30 | — | — | EP | disclosed |