Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | SCN4A | P35499 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10469654 | 1.00 | ALDH1A1 (0.36) | ALDH1A1CYP2C9MAPTCACNA1FHTR2A | |
| SCHEMBL10519147 | 0.77 | PIM1 (0.35) | ALDH1A1CYP2C9MAPTCACNA1FHTR2A | |
| SCHEMBL10468637 | 0.76 | MMP2 (0.36) | ALDH1A1CYP2C9MAPTCACNA1FHTR2A | |
| SCHEMBL7712019 | 0.76 | ALDH1A1 (0.38) | ALDH1A1CYP2C9MAPTCACNA1FHTR2A | |
| SCHEMBL7711516 | 0.73 | MMP2 (0.39) | ALDH1A1CYP2C9MAPTCACNA1FHTR2A | |
| SCHEMBL7711500 | 0.69 | LMNA (0.37) | ALDH1A1CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL7713916 | 0.69 | LMNA (0.40) | ALDH1A1MAPTLMNAGAAHPGD | |
| SCHEMBL7711675 | 0.69 | ALDH1A1 (0.34) | ALDH1A1MAPTLMNAGAAHPGD | |
| SCHEMBL745367 | 0.69 | KDM4E (0.37) | ALDH1A1CYP2C9BLMPMP22LMNA | |
| SCHEMBL7711689 | 0.69 | ALDH1A1 (0.37) | ALDH1A1MAPTCACNA1FCACNA1DCACNA1S |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4958022-A | Polycyclic compounds | BASF AKTIENGESELLSCHAFT (DE) | 1990-09-18 | — | — | US | disclosed |