Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.43 |
| ▸ | DRD1 | P21728 | 3/20 | 0.43 |
| ▸ | DRD5 | P21918 | 3/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10467274 | 0.84 | HTR1A (0.45) | HTR1A | |
| SCHEMBL10469021 | 0.80 | HTR1A (0.47) | DRD2HTR1A | |
| SCHEMBL10469020 | 0.79 | HTR2A (0.47) | — | |
| SCHEMBL10468590 | 0.78 | DRD1 (0.40) | DRD2DRD1DRD5DRD3 | |
| SCHEMBL11627187 | 0.71 | DRD2 (0.55) | DRD2DRD1DRD5DRD3 | |
| SCHEMBL10469673 | 0.69 | ADRA2A (0.49) | DRD2DRD3 | |
| SCHEMBL10467579 | 0.69 | PDE4A (0.42) | — | |
| SCHEMBL11158010 | 0.68 | L3MBTL1 (0.54) | DRD2DRD1DRD5 | |
| SCHEMBL10468525 | 0.67 | HTR2A (0.33) | — | |
| SCHEMBL10469055 | 0.66 | HTR2A (0.50) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4957914-A | ANTIDEPRESSANTS, ANXIOLYTICS, HYPOTENSIVE AGENTS | SYNTEX (U.S.A.) INC. (US) | 1990-09-18 | — | — | US | disclosed |