Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | HRH1 | P35367 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7304949 | 0.83 | HTR1A (0.52) | HTR1AALDH1A1DRD2HTR2CHTR7 | |
| SCHEMBL9035109 | 0.81 | HTR1A (0.51) | HTR1AALDH1A1DRD2HTR2CHTR7 | |
| SCHEMBL10469856 | 0.78 | HTR1A (0.39) | HTR1AALDH1A1DRD2HTR2CHTR7 | |
| SCHEMBL9034075 | 0.77 | HTR1A (0.50) | HTR1AALDH1A1DRD2HTR2CHTR7 | |
| SCHEMBL10973154 | 0.76 | FAAH (0.46) | HTR1AALDH1A1HTR7CYP1A2CYP2C9 | |
| SCHEMBL8556355 | 0.75 | HTR1A (0.55) | HTR1ADRD2HTR2CHTR7HRH1 | |
| SCHEMBL10469591 | 0.74 | HSD11B1 (0.36) | HTR1AALDH1A1DRD2HTR2CHTR7 | |
| SCHEMBL9441283 | 0.74 | HTR1A (0.54) | HTR1ADRD2HTR2CHTR7HRH1 | |
| SCHEMBL9441347 | 0.74 | HTR1A (0.54) | HTR1ADRD2HTR2CHTR7HRH1 | |
| SCHEMBL11085047 | 0.72 | HTR1A (0.39) | HTR1ADRD2HTR2CHTR7HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4956368-A | Antipsychotic agents | BRISTOL-MYERS COMPANY (US) | 1990-09-11 | — | — | US | disclosed |