Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.34 |
| ▸ | CES1 | P23141 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | F2RL1 | P55085 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15380280 | 0.84 | ALDH1A1 (0.33) | TDP1ALDH1A1TAAR1 | |
| SCHEMBL17006051 | 0.84 | GAA (0.39) | CES2CES1CA2ALDH1A1TAAR1 | |
| SCHEMBL21355814 | 0.82 | TAAR1 (0.38) | MEN1KMT2AALDH1A1TAAR1 | |
| SCHEMBL25736 | 0.82 | CA2 (0.31) | CES2CES1CA2ALDH1A1TSHR | |
| SCHEMBL16466393 | 0.82 | CYP1A2 (0.35) | — | |
| SCHEMBL702012 | 0.79 | CES2 (0.37) | CES2CES1FFAR4F2RL1MEN1 | |
| SCHEMBL2140754 | 0.79 | ERN1 (0.41) | TDP1LMNAHPGDMEN1KMT2A | |
| SCHEMBL17006127 | 0.78 | HTR2A (0.40) | LMNAMEN1KMT2ATSHRHTT | |
| SCHEMBL27744 | 0.78 | CES2 (0.44) | CES2CES1LMNAHPGDALDH1A1 | |
| SCHEMBL17006726 | 0.77 | CA1 (0.36) | CES2CES1CA2ALDH1A1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4935420-A | MICROBIOCIDES, ANTISEPTICS | OTSUKA PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-06-19 | — | — | US | disclosed |
| US-4880806-A | BACTERICIDES | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1989-11-14 | — | — | US | disclosed |
| US-4874764-A | ANTIMICROBIALS | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1989-10-17 | — | — | US | disclosed |
| US-4855292-A | ANTIMICROBIAL AGENTS | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1989-08-08 | — | — | US | disclosed |