SCHEMBL702012

SCHEMBL702012

OCc1c(F)ccc(F)c1F

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CES2 O00748 3/20 0.37
CES1 P23141 3/20 0.37
NR4A2 P43354 1/20 0.36
GABRA1 P14867 1/20 0.36
GABRG2 P18507 1/20 0.36
GABRB3 P28472 1/20 0.36
TAAR1 Q96RJ0 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
CBFB Q13951 1/20 0.32
BCHE P06276 1/20 0.31
MEP1B Q16820 1/20 0.31
CYP4F2 P78329 1/20 0.31
CYP4A11 Q02928 1/20 0.31
FFAR4 Q5NUL3 1/20 0.30
GAA P10253 1/20 0.30
GPR84 Q9NQS5 1/20 0.30
F2RL1 P55085 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1561647 0.85 TAAR1 (0.36) CES2CES1NR4A2GABRA1GABRG2
SCHEMBL4978674 0.82 MEP1B (0.46) NR4A2MEP1B
SCHEMBL634584 0.82 ALDH1A1 (0.36) NR4A2TAAR1
SCHEMBL26615986 0.82 CA3 (0.36) CES2CES1GABRA1GABRG2GABRB3
SCHEMBL3310848 0.82 CES2 (0.38) CES2CES1GABRA1GABRG2GABRB3
SCHEMBL2064221 0.80 CYP1A2 (0.33) NR4A2MEP1B
SCHEMBL13725020 0.80 NR4A2 (0.33) NR4A2CBFB
SCHEMBL616685 0.80 TAAR1 (0.41) NR4A2TAAR1KMT2AGAA
SCHEMBL1166843 0.80 ENPP2 (0.33) NR4A2GABRA1GABRG2GABRB3CYP4F2
SCHEMBL5425835 0.80 CYP1A2 (0.33) CES2CES1GABRA1GABRG2GABRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8952083-B2 Fluorocopolymer composition and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2015-02-10 US claimed
WO-2010002175-A2 RESIN COMPOSITION FOR CLADDING OF OPTICAL FIBER SSCP CO., LTD. (KR) 2010-01-07 WO claimed
US-20250313526-A1 PYRETHROID COMPOUND CONTAINING DOUBLE BONDS AND CYANO GROUPS, SYNTHESIS METHOD THEREFOR, AND APPLICATION THEREOF JIANGSU YANGNONG CHEMICAL CO., LTD. (CN) 2025-10-09 US disclosed
EP-4484407-A2 (METH)ACRYLATE COMPOUND, ADDITIVE FOR OPTICAL RESIN, OPTICAL ELEMENT, AND OPTICAL DEVICE NIKON CORPORATION (JP) 2025-01-01 EP disclosed
CN-116082563-B (Meth) acrylate compound, optical resin additive, optical element, and optical device 株式会社 尼康 2024-09-20 CN disclosed
CN-118359760-A Optical resin, optical element, and optical device 株式会社 尼康 2024-07-19 CN disclosed
WO-2023160316-A1 PYRETHROID COMPOUND CONTAINING DOUBLE BONDS AND CYANO GROUPS, SYNTHESIS METHOD THEREFOR, AND APPLICATION THEREOF 江苏扬农化工股份有限公司 2023-08-31 WO disclosed
CN-116375604-A Double-bond cyano-containing pyrethroid compound, and synthetic method and application thereof 江苏扬农化工股份有限公司 2023-07-04 CN disclosed
CN-116082563-A (meth) acrylate compound, optical resin additive, optical element, and optical device 株式会社 尼康 2023-05-09 CN disclosed
US-11289238-B2 Compositions for the filling of high aspect ratio vertical interconnect access (VIA) holes HERAEUS PRECIOUS METALS NORTH AMERICA CONSHOHOCKEN LLC (US) 2022-03-29 US disclosed
US-11142636-B2 (Meth)acrylate compound, additive for optical resin, optical element, and optical device NIKON CORPORATION (JP) 2021-10-12 US disclosed
US-6022899-A EFFECTIVE INHIBITORS OF THE CELLULAR SODIUM PROTON ANTIPORTER HOECHST AKTIENGESELLSCHAFT (DE) 2000-02-08 US disclosed
US-5753710-A INHIBITORS OF THE CELLULAR SODIUM PROTON ANTIPORTER HOECHST AKTIENGESELLSCHAFT (DE) 1998-05-19 US disclosed
EP-0748795-A2 Substituted benzyloxycarbonyl guanidines as Na+/H+ exchange inhibitors, process for their preparation, their use as medicinal or diagnostic agents as well as medicament containing them HOECHST AKTIENGESELLSCHAFT (DE) 1996-12-18 EP disclosed
US-5340835-A Insecticides ROUSSEL-UCLAF (FR) 1994-08-23 US disclosed
US-5336670-A 2,2-dimethyl-3-(but-1-en-3-ynyl)-cyclopropane carboxylates ROUSSEL-UCLAF (FR) 1994-08-09 US disclosed
US-4935420-A MICROBIOCIDES, ANTISEPTICS OTSUKA PHARMACEUTICAL COMPANY, LTD. (JP) 1990-06-19 US disclosed
US-4880806-A BACTERICIDES OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1989-11-14 US disclosed
US-4874764-A ANTIMICROBIALS OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1989-10-17 US disclosed
US-4855292-A ANTIMICROBIAL AGENTS OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1989-08-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250313526-A1 PYRETHROID COMPOUND CONTAINING DOUBLE BONDS AND CYANO GROUPS, SYNTHESIS METHOD THEREFOR, AND APPLICATION THEREOF NOTUM, DDT, CYP4F11 CES2 482/4885CES1 233/4885NR4A2 2879/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.