Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 11/20 | 0.61 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10473903 | 0.86 | HSD11B1 (0.49) | HSD11B1P2RX7GAAATMMAPK13 | |
| SCHEMBL10592226 | 0.79 | HSD11B1 (0.54) | HSD11B1P2RX7GAAATMMAPK13 | |
| SCHEMBL10474202 | 0.77 | HSD11B1 (0.43) | HSD11B1GAAATMMAPK14 | |
| SCHEMBL2746936 | 0.76 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL10594058 | 0.75 | HSD11B1 (0.49) | HSD11B1P2RX7MAPK13MAPK12MAPK11 | |
| SCHEMBL10595099 | 0.75 | HSD11B1 (0.49) | HSD11B1P2RX7MAPK13MAPK12MAPK11 | |
| SCHEMBL10473973 | 0.73 | HSD11B1 (0.46) | HSD11B1P2RX7MAPK13MAPK12MAPK11 | |
| SCHEMBL9829408 | 0.70 | HSD11B1 (0.67) | HSD11B1 | |
| SCHEMBL10593189 | 0.68 | HSD11B1 (0.41) | HSD11B1P2RX7LMNA | |
| SCHEMBL10473910 | 0.68 | MGLL (0.40) | HSD11B1P2RX7MAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4943583-A | PESTICIDES | HOFFMANN-LA ROCHE INC. (US) | 1990-07-24 | — | — | US | disclosed |
| EP-0270061-A2 | Five-membered heterocycles with three heteroatoms, their preparation and their use as pesticides | CIBA-GEIGY AG (CH) | 1988-06-08 | — | — | EP | disclosed |