Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 5/20 | 0.37 |
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10473909 | 0.85 | HSD11B1 (0.43) | HSD11B1SCN9AALDH1A1L3MBTL1KCNN4 | |
| SCHEMBL10475020 | 0.82 | ALDH1A1 (0.38) | HSD11B1SCN9AALDH1A1L3MBTL1GAA | |
| SCHEMBL10474167 | 0.82 | JAK2 (0.43) | ALDH1A1L3MBTL1KCNN4HCAR1 | |
| SCHEMBL10475264 | 0.78 | HCAR1 (0.39) | SCN9AALDH1A1GAAATMDHODH | |
| SCHEMBL10474147 | 0.77 | HSD11B1 (0.61) | HSD11B1GAAATMMAPK14 | |
| SCHEMBL10474070 | 0.74 | CDK4 (0.38) | ALDH1A1GAAATMDHODHMAPK14 | |
| SCHEMBL10473916 | 0.74 | JAK2 (0.40) | HSD11B1ALDH1A1L3MBTL1GAAATM | |
| SCHEMBL10595769 | 0.74 | ALDH1A1 (0.40) | HSD11B1SCN9AALDH1A1L3MBTL1GAA | |
| SCHEMBL10475055 | 0.73 | MGLL (0.41) | SCN9AALDH1A1L3MBTL1KCNN4POLB | |
| SCHEMBL10475137 | 0.73 | MAPT (0.41) | SCN9AALDH1A1L3MBTL1GAAATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4943583-A | PESTICIDES | HOFFMANN-LA ROCHE INC. (US) | 1990-07-24 | — | — | US | disclosed |
| EP-0270061-A2 | Five-membered heterocycles with three heteroatoms, their preparation and their use as pesticides | CIBA-GEIGY AG (CH) | 1988-06-08 | — | — | EP | disclosed |