Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.39 |
| ▸ | MAT2A | P31153 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10475390 | 0.80 | MAPT (0.53) | KMT2AMAPTMAT2AL3MBTL1GAA | |
| SCHEMBL10475286 | 0.78 | KCNN4 (0.48) | KMT2AMAPTTP53NPC1HPGD | |
| SCHEMBL10475151 | 0.78 | HSD11B1 (0.42) | KMT2AHSD11B1MAPTTP53NPC1 | |
| SCHEMBL10475153 | 0.75 | MAPT (0.40) | KMT2AHSD11B1MAPTTP53NPC1 | |
| SCHEMBL8763552 | 0.74 | NPC1 (0.47) | KMT2AMAPTTP53NPC1HPGD | |
| SCHEMBL10473913 | 0.74 | ELANE (0.43) | KMT2AHSD11B1MAPTTP53NPC1 | |
| SCHEMBL10474081 | 0.73 | KCNN4 (0.48) | MAPTTP53NOTUMC1R | |
| SCHEMBL10475127 | 0.72 | NPBWR1 (0.44) | MAPTTP53NPC1HPGDRAB9A | |
| SCHEMBL10473978 | 0.72 | MAPT (0.45) | KMT2AHSD11B1MAPTTP53NPC1 | |
| SCHEMBL10474068 | 0.71 | MAPT (0.51) | KMT2AMAPTNOTUMMAT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4943583-A | PESTICIDES | HOFFMANN-LA ROCHE INC. (US) | 1990-07-24 | — | — | US | disclosed |
| EP-0270061-A2 | Five-membered heterocycles with three heteroatoms, their preparation and their use as pesticides | CIBA-GEIGY AG (CH) | 1988-06-08 | — | — | EP | disclosed |