Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.54 |
| ▸ | CHRNA7 | P36544 | 10/20 | 0.50 |
| ▸ | SNCA | P37840 | 2/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL1044358 | 0.97 | LTA4H (0.54) | LTA4HCHRNA7SNCA | |
| Hydrochloric Acid SCHEMBL1046793 | 0.97 | LTA4H (0.54) | LTA4HCHRNA7SNCA | |
| SCHEMBL8378569 | 0.92 | LTA4H (0.50) | LTA4HCHRNA7SNCA | |
| Bromide SCHEMBL5571267 | 0.92 | LTA4H (0.55) | LTA4HCHRNA7SNCA | |
| SCHEMBL8372241 | 0.92 | LTA4H (0.50) | LTA4HCHRNA7SNCA | |
| SCHEMBL1045377 | 0.92 | LTA4H (0.50) | LTA4HCHRNA7SNCA | |
| SCHEMBL3694644 | 0.90 | LTA4H (0.47) | LTA4HCHRNA7SNCA | |
| Acetic Acid SCHEMBL1042649 | 0.89 | LTA4H (0.46) | LTA4H | |
| Bromide SCHEMBL9336662 | 0.87 | KCNA3 (0.55) | LTA4HCHRNA7SNCA | |
| Iodide SCHEMBL7909299 | 0.87 | LTA4H (0.52) | LTA4HCHRNA7SNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8530617-B2 | Silicon-containing particle, process for producing the same, organic-polymer composition, ceramic, and process for producing the same | DOW CORNING TORAY COMPANY, LTD. (JP) | 2013-09-10 | — | — | US | disclosed |
| US-8450231-B2 | Silicon-containing particles, method for manufacturing thereof, oil composition, ceramic material, and method for manufacturing thereof | DOW CORNING TORAY COMPANY, LTD. (JP) | 2013-05-28 | — | — | US | disclosed |
| EP-2461397-A1 | ELECTRODE ACTIVE MATERIAL, ELECTRODE, AND ELECTRICITY STORAGE DEVICE | Dow Corning Toray Co., Ltd. (JP) | 2012-06-06 | — | — | EP | disclosed |
| US-20120121981-A1 | Electrode Active Material, Electrode, And Electricity Storage Device | DOW CORNING TORAY CO., LTD. (JP) | 2012-05-17 | — | — | US | disclosed |
| US-20110045963-A1 | Silicon-Containing Particles, Method For Manufacturing Thereof, Oil Composition, Ceramic Material, And Method For Manufacturing Thereof | DOW CORNING TORAY COMPANY, LTD. (JP) | 2011-02-24 | — | — | US | disclosed |
| US-20110033708-A1 | Silicon-Containing Particle, Process For Producing The Same, Organic-Polymer Composition, Ceramic, And Process For Producing The Same | DOW CORNING TORAY COMPANY, LTD. (JP) | 2011-02-10 | — | — | US | disclosed |
| EP-2271702-A2 | SILICON-CONTAINING PARTICLES, METHOD FOR MANUFACTURING THEREOF, OIL COMPOSITION, CERAMIC MATERIAL, AND METHOD FOR MANUFACTURING THEREOF | Dow Corning Toray Co., Ltd. (JP) | 2011-01-12 | — | — | EP | disclosed |
| EP-2241586-A1 | SILICON-CONTAINING PARTICLE, PROCESS FOR PRODUCING THE SAME, ORGANIC-POLYMER COMPOSITION, CERAMIC, AND PROCESS FOR PRODUCING THE SAME | Dow Corning Toray Co., Ltd. (JP) | 2010-10-20 | — | — | EP | disclosed |
| WO-2009133765-A2 | SILICON-CONTAINING PARTICLES, METHOD FOR MANUFACTURING THEREOF, OIL COMPOSITION, CERAMIC MATERIAL, AND METHOD FOR MANUFACTURING THEREOF | DOW CORNING TORAY CO., LTD. (JP) | 2009-11-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110033708-A1 | Silicon-Containing Particle, Process For Producing The Same, Organic-Polymer Composition, Ceramic, And Process For Producing The Same | SKP1, SPOP, SSRP1 | LTA4H 1815/4885CHRNA7 3393/4885SNCA 1754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.