Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | SNCA | P37840 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | NQO1 | P15559 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3156511 | 0.97 | LTA4H (0.52) | LTA4HSNCAMEN1KMT2AL3MBTL1 | |
| Bromide SCHEMBL2449254 | 0.97 | SNCA (0.53) | LTA4HSNCAMEN1KMT2AL3MBTL1 | |
| Water SCHEMBL8527845 | 0.97 | LTA4H (0.52) | LTA4HSNCAMEN1KMT2AL3MBTL1 | |
| SCHEMBL8375288 | 0.92 | LTA4H (0.47) | LTA4HSNCAMEN1KMT2AL3MBTL1 | |
| SCHEMBL8372239 | 0.92 | LTA4H (0.47) | LTA4HSNCAMEN1KMT2AL3MBTL1 | |
| Iodide SCHEMBL1047429 | 0.87 | LTA4H (0.54) | LTA4HSNCACHRNA7 | |
| Bromide SCHEMBL1044358 | 0.83 | LTA4H (0.54) | LTA4HSNCACHRNA7SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL1046793 | 0.83 | LTA4H (0.54) | LTA4HSNCACHRNA7 | |
| SCHEMBL8375290 | 0.83 | SNCA (0.42) | LTA4HSNCAMEN1KMT2AL3MBTL1 | |
| Bromide SCHEMBL28338224 | 0.83 | CALM1 (0.43) | SNCAMEN1KMT2ASIGMAR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326066-B1 | CHEMICAL STABILITY, LOW VISCOSITY, HIGH DIELECTRIC ANISOTROPY, ULTRAVIOLET AND TEMPERATURE STABILITY; USED IN ELECTROOPTICS | MERCK PATENT GESELLSCHAFT MIT RESCHANKTER HAFTUNG (DE) | 2001-12-04 | — | — | US | disclosed |
| US-6200654-B1 | ELECTROOPTIC DISPLAYING | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2001-03-13 | — | — | US | disclosed |