SCHEMBL10474669

SCHEMBL10474669

Cc1[c]cc(C(C)(C)CC(C)(C)C)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.48
CYP3A4 P08684 3/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
CYP2D6 P10635 2/20 0.35
HIF1A Q16665 1/20 0.35
MEN1 O00255 2/20 0.32
USP2 O75604 2/20 0.32
TP53 P04637 2/20 0.32
MAPT P10636 2/20 0.32
KMT2A Q03164 2/20 0.32
ESR1 P03372 1/20 0.32
PGR P06401 1/20 0.32
ADORA3 P0DMS8 1/20 0.32
AR P10275 1/20 0.32
DRD1 P21728 1/20 0.32
PTGS1 P23219 1/20 0.32
SLC6A2 P23975 1/20 0.32
PDE4A P27815 1/20 0.32
MAPK1 P28482 1/20 0.32
CASP1 P29466 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL225079 0.80 SHBG (0.48) SHBGCYP3A4SMN1; SMN2CYP2D6HIF1A
SCHEMBL930516 0.78 SHBG (0.57) SHBGCYP3A4SMN1; SMN2CYP2D6HIF1A
SCHEMBL1550638 0.76 TSHR (0.46) MEN1MAPTKMT2AMAPK1LMNA
SCHEMBL10474670 0.74 CNR2 (0.50)
SCHEMBL8683078 0.72 SHBG (0.41) SHBGCYP3A4SMN1; SMN2CYP2D6HIF1A
SCHEMBL8768818 0.72 SHBG (0.64) SHBGCYP3A4SMN1; SMN2CYP2D6HIF1A
SCHEMBL11817162 0.71 SHBG (0.42) SHBGCYP3A4SMN1; SMN2CYP2D6HIF1A
SCHEMBL21138351 0.70 SHBG (0.68) SHBGCYP3A4SMN1; SMN2CYP2D6HIF1A
SCHEMBL192799 0.70 ALDH1A1 (0.35) MAPTTSHRALDH1A1
SCHEMBL10514413 0.70 SMN1; SMN2 (0.42) SHBGCYP3A4SMN1; SMN2CYP2D6HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4910124-A Pyrazoloazole coupler FUJI PHOTO FILM CO., LTD. (JP) 1990-03-20 US disclosed
EP-0234428-A2 Color image-forming process FUJI PHOTO FILM CO., LTD. (JP) 1987-09-02 EP disclosed