SCHEMBL8683078

SCHEMBL8683078

CCCCc1[c]cc(C(C)(C)CC(C)(C)C)cc1

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.41
CYP3A4 P08684 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
CYP2D6 P10635 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8683079 0.84 CNR2 (0.44)
SCHEMBL6014093 0.78 MEN1 (0.36) CYP3A4SMN1; SMN2
SCHEMBL7635289 0.77 GHSR (0.40) SHBGCYP3A4SMN1; SMN2HIF1A
SCHEMBL8469756 0.75 CYP3A4 (0.45) SHBGCYP3A4SMN1; SMN2CYP2D6HIF1A
SCHEMBL5145878 0.73 CYP3A4 (0.40) SHBGCYP3A4SMN1; SMN2HIF1A
SCHEMBL10474669 0.72 SHBG (0.48) SHBGCYP3A4SMN1; SMN2CYP2D6HIF1A
SCHEMBL225079 0.72 SHBG (0.48) SHBGCYP3A4SMN1; SMN2CYP2D6HIF1A
SCHEMBL21268399 0.72
SCHEMBL930516 0.70 SHBG (0.57) SHBGCYP3A4SMN1; SMN2CYP2D6HIF1A
SCHEMBL4625366 0.70 HTT (0.33) SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5756274-A IMAGES AND PHOTOGRAPHY WITH MULTILAYER ELEMENTS AND MULTICOLOR COUPLERS AND OXIDIZED PRODUCT OF AROMATIC PRIMARY AMINE FUJI PHOTO FILM CO., LTD. (JP) 1998-05-26 US disclosed