Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 5/20 | 0.37 |
| ▸ | AR | P10275 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3281904 | 0.82 | NPC1 (0.38) | SHBGCYP3A4SMN1; SMN2ESR1AR | |
| SCHEMBL10474669 | 0.78 | SHBG (0.48) | SHBGCYP3A4SMN1; SMN2HIF1ACYP2D6 | |
| SCHEMBL225079 | 0.78 | SHBG (0.48) | SHBGCYP3A4SMN1; SMN2HIF1ACYP2D6 | |
| SCHEMBL1639237 | 0.77 | LMNA (0.48) | CYP3A4SMN1; SMN2CYP2D6ESR1AR | |
| SCHEMBL930517 | 0.75 | CNR2 (0.47) | — | |
| SCHEMBL31282065 | 0.73 | SHBG (1.00) | SHBGCYP3A4SMN1; SMN2HIF1ACYP2D6 | |
| SCHEMBL10141 | 0.73 | SHBG (1.00) | SHBGCYP3A4SMN1; SMN2HIF1ACYP2D6 | |
| SCHEMBL10785821 | 0.71 | SHBG (0.95) | SHBGCYP3A4SMN1; SMN2HIF1ACYP2D6 | |
| SCHEMBL22773183 | 0.71 | SHBG (0.95) | SHBGCYP3A4SMN1; SMN2HIF1ACYP2D6 | |
| Hydrogen Sulfide SCHEMBL10824257 | 0.71 | SHBG (0.95) | SHBGCYP3A4SMN1; SMN2HIF1ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107778647-A | A kind of polypropylene alloy of high optical reflectance and preparation method thereof | 合肥杰事杰新材料股份有限公司 | 2018-03-09 | — | — | CN | claimed |
| CN-107778648-A | A kind of white PP alloys of high light-proofness and preparation method thereof | 合肥杰事杰新材料股份有限公司 | 2018-03-09 | — | — | CN | claimed |
| CN-106883661-A | The UV and IR barrier coating and preparation method of a kind of sponge brush application | 深圳市捷源环保科技有限公司 | 2017-06-23 | — | — | CN | claimed |
| CN-106459555-B | Composition for manufacturing an ophthalmic lens comprising a UV absorber and an anti-yellowing additive | 依视路国际公司 | 2019-03-22 | — | — | CN | disclosed |
| CN-108623930-A | A kind of polystyrene microsphere composite material and preparation method for rapid shaping | 合肥杰事杰新材料股份有限公司 | 2018-10-09 | — | — | CN | disclosed |
| CN-105968771-B | High fire-retardance high intensity highly reflective polycarbonate material and its preparation method and application | 中广核俊尔新材料有限公司 | 2018-04-10 | — | — | CN | disclosed |
| CN-104805872-B | Red mud Tailings Dam composite anti-penetrating structure | 重庆交通大学 | 2018-01-30 | — | — | CN | disclosed |
| CN-106811150-A | A kind of photovoltaic component encapsulating glued membrane of high reflection polymer microballoon filling and preparation method thereof | 宁波卓胜新材料有限公司 | 2017-06-09 | — | — | CN | disclosed |
| US-9631048-B2 | Sulfonium compounds, their preparation and use | BASF SE (DE) | 2017-04-25 | — | — | US | disclosed |
| CN-104818733-B | Red mud dump leakage preventing structure | 重庆交通大学 | 2017-03-15 | — | — | CN | disclosed |
| CN-106459412-A | Fiber reinforced polyetherimide compositions | 沙特基础工业全球技术公司 | 2017-02-22 | — | — | CN | disclosed |
| WO-2012113829-A1 | SULFONIUM SULFATES, THEIR PREPARATION AND USE | BASF SE (DE) | 2012-08-30 | — | — | WO | disclosed |
| US-20110172457-A1 | TETRAKIS(ETHER-SUBSTITUTED FORMYLPHENYL) AND NEW POLYNUCLEAR POLYPHENOL DERIVED FROM THE SAME | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2011-07-14 | — | — | US | disclosed |
| US-20110028752-A1 | NOVEL BIS(FORMYLPHENYL) COMPOUND AND NOVEL POLYNUCLEAR POLYPHENOL COMPOUND DERIVED FROM THE SAME | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2011-02-03 | — | — | US | disclosed |
| US-7875743-B2 | such as bis(3-formyl-4-(4-methoxycarbonylphenyl)methoxyphenyl)methane, by reacting bis(hydroxymethyl-hydroxyphenyl)alkane with hexamethylene tetramine in presence of acid and hydrolyzing, then reacting with halogenated alkoxycarbonyl hydrocarbon in presence of base | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2011-01-25 | — | — | US | disclosed |
| US-7858819-B2 | Tris(formylphenyl) and novel polynuclear phenol derived therefrom | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-12-28 | — | — | US | disclosed |
| US-20100099908-A1 | TRIS(FORMYLPHENYL) AND NEW POLYNUCLEAR POLYPHENOL DERIVED THEREFROM | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-04-22 | — | — | US | disclosed |
| US-20100016633-A1 | such as bis(3-formyl-4-(4-methoxycarbonylphenyl)methoxyphenyl)methane, by reacting bis(hydroxymethyl-hydroxyphenyl)alkane with hexamethylene tetramine in presence of acid and hydrolyzing, then reacting with halogenated alkoxycarbonyl hydrocarbon in presence of base | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-01-21 | — | — | US | disclosed |
| US-4933355-A | ALDOSE REDUCTASE INHIBITORS | SANKYO COMPANY LIMITED (JP) | 1990-06-12 | — | — | US | disclosed |
| EP-0337819-A1 | Thiazole derivatives, their preparation and their use in the treatment of diabetes complications | Sankyo Company Limited (JP) | 1989-10-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028752-A1 | NOVEL BIS(FORMYLPHENYL) COMPOUND AND NOVEL POLYNUCLEAR POLYPHENOL COMPOUND DERIVED FROM THE SAME | PAH, PCBP1, MLLT1 | SHBG 3022/4885CYP3A4 460/4885SMN1; SMN2 2621/4885 |
| US-20110172457-A1 | TETRAKIS(ETHER-SUBSTITUTED FORMYLPHENYL) AND NEW POLYNUCLEAR POLYPHENOL DERIVED FROM THE SAME | AHR, PAH, ARNT | SHBG 1452/4885CYP3A4 526/4885SMN1; SMN2 3118/4885 |
| US-20100099908-A1 | TRIS(FORMYLPHENYL) AND NEW POLYNUCLEAR POLYPHENOL DERIVED THEREFROM | AS3MT, RRM2, SHROOM3 | SHBG 1626/4885CYP3A4 940/4885SMN1; SMN2 2165/4885 |
| US-20100016633-A1 | such as bis(3-formyl-4-(4-methoxycarbonylphenyl)methoxyphenyl)methane, by reacting bis(hydroxymethyl-hydroxyphenyl)alkane with hexamethylene tetramine in presence of acid and hydrolyzing, then reacting with halogenated alkoxycarbonyl hydrocarbon in presence of base | PAH, PGM2, HNMT | SHBG 2845/4885CYP3A4 257/4885SMN1; SMN2 3339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.