Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10474764 | 0.87 | P2RX7 (0.44) | CYP2C19CYP3A4CAPN1P2RX7ALDH1A1 | |
| SCHEMBL10475650 | 0.79 | MTNR1A (0.44) | CYP2C9CYP2C19CAPN1P2RX7ALDH1A1 | |
| SCHEMBL21869824 | 0.78 | FKBP1A (0.53) | CAPN1P2RX7HDAC1HDAC2HDAC6 | |
| SCHEMBL28663248 | 0.78 | FKBP1A (0.53) | CAPN1P2RX7HDAC1HDAC2HDAC6 | |
| SCHEMBL31706270 | 0.77 | IL1RN (0.50) | CYP2C9CYP2C19CAPN1P2RX7HDAC1 | |
| SCHEMBL27939222 | 0.77 | HCRTR1 (0.44) | P2RX7HDAC1HDAC2HDAC6HCRTR1 | |
| SCHEMBL27939223 | 0.77 | HCRTR1 (0.44) | P2RX7HDAC1HDAC2HDAC6HCRTR1 | |
| SCHEMBL31706028 | 0.76 | ITGB1 (0.47) | CYP2C19CYP3A4CAPN1P2RX7HDAC1 | |
| SCHEMBL10785525 | 0.76 | MEN1 (0.46) | CYP2C9CYP2C19CYP3A4P2RX7HDAC1 | |
| SCHEMBL7275104 | 0.76 | HCRTR1 (0.47) | CYP2C19CYP3A4CAPN1P2RX7HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990012787-A1 | ENANTIOMER-PURE 5-OXO-2-PYRROLIDINE-PROPANE ACIDS ALKYLATED IN POSITION 1 AND THEIR ESTERS; THEIR PRODUCTION AND USE | FLEISCHHACKER WILHELM (AT) | 1990-11-01 | — | — | WO | claimed |
| WO-1990012787-A1 | ENANTIOMER-PURE 5-OXO-2-PYRROLIDINE-PROPANE ACIDS ALKYLATED IN POSITION 1 AND THEIR ESTERS; THEIR PRODUCTION AND USE | FLEISCHHACKER WILHELM (AT) | 1990-11-01 | — | — | WO | disclosed |