Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 6/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 6/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10474764 | 0.88 | P2RX7 (0.44) | MTNR1AALDH1A1TSHRCYP2C19HCRTR1 | |
| SCHEMBL31706028 | 0.79 | ITGB1 (0.47) | MTNR1ATSHRCYP2C19HCRTR1HCRTR2 | |
| SCHEMBL30829326 | 0.79 | HCRTR1 (0.47) | MTNR1ATSHRCYP2C19HCRTR1HCRTR2 | |
| SCHEMBL9456538 | 0.79 | TP53 (0.45) | MTNR1AALDH1A1TSHRCYP2C19HCRTR1 | |
| SCHEMBL7275111 | 0.79 | HCRTR1 (0.47) | MTNR1ATSHRCYP2C19HCRTR1HCRTR2 | |
| SCHEMBL7275104 | 0.79 | HCRTR1 (0.47) | MTNR1ATSHRCYP2C19HCRTR1HCRTR2 | |
| SCHEMBL10474756 | 0.79 | CYP2C9 (0.44) | MTNR1AALDH1A1CYP2D6CYP2C9TSHR | |
| SCHEMBL31705403 | 0.77 | ITGB1 (0.46) | MTNR1AALDH1A1CYP2D6CYP2C9TSHR | |
| SCHEMBL6703838 | 0.77 | TP53 (0.46) | MTNR1AALDH1A1TSHRCYP2C19HCRTR1 | |
| SCHEMBL10475651 | 0.77 | PTGER4 (0.46) | MTNR1AP2RX7MTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990012787-A1 | ENANTIOMER-PURE 5-OXO-2-PYRROLIDINE-PROPANE ACIDS ALKYLATED IN POSITION 1 AND THEIR ESTERS; THEIR PRODUCTION AND USE | FLEISCHHACKER WILHELM (AT) | 1990-11-01 | — | — | WO | disclosed |