Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TET2 | Q6N021 | 5/20 | 0.34 |
| ▸ | TET3 | O43151 | 1/20 | 0.34 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1047505 | 1.00 | ALOX15 (0.39) | ALOX15ALDH1A1CYP2D6HSD17B10TET2 | |
| SCHEMBL11241202 | 0.89 | ALOX15 (0.47) | ALOX15ALDH1A1CYP2D6HSD17B10TET2 | |
| SCHEMBL11126445 | 0.89 | ALOX15 (0.47) | ALOX15ALDH1A1CYP2D6HSD17B10TET2 | |
| SCHEMBL2223054 | 0.81 | TET2 (0.37) | ALOX15ALDH1A1CYP2D6HSD17B10TET2 | |
| SCHEMBL11291369 | 0.78 | TDP1 (0.38) | ALOX15ALDH1A1CYP2D6HSD17B10TET2 | |
| SCHEMBL11291372 | 0.78 | TDP1 (0.38) | ALOX15ALDH1A1CYP2D6HSD17B10TET2 | |
| SCHEMBL2119437 | 0.78 | ALDH1A1 (0.39) | ALOX15ALDH1A1CYP2D6HSD17B10TET2 | |
| SCHEMBL5669666 | 0.78 | ALOX15 (0.33) | ALOX15ALDH1A1CYP2D6HSD17B10 | |
| SCHEMBL87513 | 0.77 | — | — | |
| SCHEMBL18277281 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8951616-B2 | Ester group containing liquid crystals for optical or electro optical devices | ROLIC AG (CH) | 2015-02-10 | — | — | US | disclosed |
| EP-2451892-B1 | ESTER GROUP CONTAINING LIQUID CRYSTALS FOR OPTICAL OR ELECTRO OPTICAL DEVICES | ROLIC AG (CH) | 2013-11-20 | — | — | EP | disclosed |
| EP-2451892-A1 | ESTER GROUP CONTAINING LIQUID CRYSTALS FOR OPTICAL OR ELECTRO OPTICAL DEVICES | Rolic AG (CH) | 2012-05-16 | — | — | EP | disclosed |
| US-20120114907-A1 | ESTER GROUP CONTAINING LIQUID CRYSTALS FOR OPTICAL OR ELECTRO OPTICAL DEVICES | ROLIC AG. (CH) | 2012-05-10 | — | — | US | disclosed |
| WO-2011003846-A1 | ESTER GROUP CONTAINING LIQUID CRYSTALS FOR OPTICAL OR ELECTRO OPTICAL DEVICES | ROLIC AG (CH) | 2011-01-13 | — | — | WO | disclosed |
| EP-2272937-A1 | Ester group containing compounds for optical or electro optical devices | Rolic AG (CH) | 2011-01-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120114907-A1 | ESTER GROUP CONTAINING LIQUID CRYSTALS FOR OPTICAL OR ELECTRO OPTICAL DEVICES | MLEC, CEL, AQP4 | ALOX15 480/4885ALDH1A1 2167/4885CYP2D6 3465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.