Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 8/20 | 0.49 |
| ▸ | CCR1 | P32246 | 1/20 | 0.49 |
| ▸ | CCR5 | P51681 | 1/20 | 0.49 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.49 |
| ▸ | NAAA | Q02083 | 10/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6135727 | 0.82 | NAAA (0.40) | CCR2CCR1CCR5CXCR4NAAA | |
| SCHEMBL5699633 | 0.78 | CCR2 (0.40) | CCR2CCR1CCR5CXCR4 | |
| SCHEMBL10476331 | 0.78 | CCR2 (0.44) | CCR2CCR1CCR5CXCR4 | |
| SCHEMBL5699632 | 0.78 | CCR2 (0.52) | CCR2CCR1CCR5CXCR4NAAA | |
| SCHEMBL1114657 | 0.78 | CCR2 (0.52) | CCR2CCR1CCR5CXCR4NAAA | |
| SCHEMBL5699622 | 0.78 | CCR2 (0.52) | CCR2CCR1CCR5CXCR4NAAA | |
| SCHEMBL1114788 | 0.78 | CCR2 (0.52) | CCR2CCR1CCR5CXCR4NAAA | |
| SCHEMBL1114780 | 0.75 | NAAA (0.55) | CCR2NAAAGAAMAPK1HTT | |
| SCHEMBL718704 | 0.74 | CCR2 (0.63) | CCR2CCR1CCR5CXCR4 | |
| SCHEMBL1114798 | 0.74 | CCR2 (0.63) | CCR2CCR1CCR5CXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1691814-A2 | ANTI-INFLAMMATORY AGENTS | CAMBRIDGE UNIVERSITY TECHNICAL SERVICES LIMITED (GB) | 2006-08-23 | — | — | EP | claimed |