SCHEMBL10477183

SCHEMBL10477183

CCC(=S)N(C=O)c1cccc(OC)c1

nearest known ligand 0.52

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.52
MTNR1A P48039 12/20 0.45
MTNR1B P49286 12/20 0.45
MAPT P10636 1/20 0.43
ESR1 P03372 1/20 0.43
HSD17B2 P37059 2/20 0.40
HSD17B1 P14061 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2556980 0.73 ALOX15 (0.45) ALOX15MTNR1AMTNR1BHSD17B2HSD17B1
SCHEMBL28255210 0.72 ALOX15 (0.55) ALOX15MTNR1AMTNR1BHSD17B2HSD17B1
SCHEMBL26624253 0.71 MTNR1A (0.53) ALOX15MTNR1AMTNR1BESR1HSD17B2
SCHEMBL4522245 0.71 ALOX15 (0.70) ALOX15MTNR1AMTNR1BESR1
SCHEMBL27522069 0.70 ALOX15 (0.54) ALOX15MTNR1AMTNR1BESR1HSD17B2
SCHEMBL14543537 0.70 HSD17B2 (0.57) ALOX15MTNR1AMTNR1BHSD17B2HSD17B1
SCHEMBL27842446 0.69 ALOX15 (0.56) ALOX15MTNR1AMTNR1BESR1
SCHEMBL12837169 0.68 MTNR1A (0.54) ALOX15MTNR1AMTNR1BESR1HSD17B2
SCHEMBL10477162 0.68 ALOX15 (0.51) ALOX15MTNR1AMTNR1BESR1HSD17B2
SCHEMBL29914685 0.68 ALDH1A1 (0.55) ALOX15MTNR1AMTNR1BMAPTESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4880831-A META SUBSTITUTED ETHERS STAUFFER CHEMICAL COMPANY (US) 1989-11-14 US disclosed
US-4797416-A APPLYING TO PLANTS STAUFFER CHEMICAL CO. (US) 1989-01-10 US disclosed
EP-0274271-A1 Fungicidal carbanilates, process for the production thereof, compositions containing them and method of use thereof STAUFFER AGRICULTURAL CHEMICALS COMPANY, INC. (US) 1988-07-13 EP disclosed