Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 3/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.44 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | AGPAT2 | O15120 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10477441 | 0.80 | CASP3 (0.43) | CASP3SENP7FFAR2TP53MAPT | |
| SCHEMBL11065324 | 0.77 | MAPT (0.46) | CASP3SENP7TP53MAPTANO1 | |
| SCHEMBL11077235 | 0.77 | TP53 (0.46) | CASP3SENP7TP53MAPTANO1 | |
| SCHEMBL10829015 | 0.76 | MAOB (0.52) | CASP3SENP7TP53MAPTANO1 | |
| SCHEMBL5095572 | 0.74 | MEN1 (0.51) | CASP3SENP7FFAR2TP53MAPT | |
| SCHEMBL10829024 | 0.74 | MAPT (0.56) | CASP3SENP7FFAR2TP53MAPT | |
| SCHEMBL27654631 | 0.73 | MAPT (0.58) | CASP3SENP7FFAR2TP53MAPT | |
| SCHEMBL11076330 | 0.73 | XDH (0.49) | CASP3SENP7TP53MAPTNPSR1 | |
| SCHEMBL11065025 | 0.72 | MAPT (0.43) | CASP3SENP7FFAR2TP53MAPT | |
| Eclazolast SCHEMBL636302 | 0.71 | MEN1 (0.46) | CASP3SENP7TP53MAPTANO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4490373-A | BENZOXAZOLE-2-CARBOXYLIC ACID AMIDES | USV PHARMACEUTICAL CORPORATION (US) | 1984-12-25 | — | — | US | claimed |
| EP-0127066-A2 | Composition for treating asthma | USV PHARMACEUTICAL CORPORATION (US) | 1984-12-05 | — | — | EP | claimed |
| US-4490373-A | BENZOXAZOLE-2-CARBOXYLIC ACID AMIDES | USV PHARMACEUTICAL CORPORATION (US) | 1984-12-25 | — | — | US | disclosed |
| EP-0127066-A2 | Composition for treating asthma | USV PHARMACEUTICAL CORPORATION (US) | 1984-12-05 | — | — | EP | disclosed |