Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.48 |
| ▸ | MME | P08473 | 2/20 | 0.46 |
| ▸ | ACE | P12821 | 2/20 | 0.46 |
| ▸ | CPA1 | P15085 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | MMP8 | P22894 | 2/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10477661 | 0.86 | CTNNB1 (0.50) | ALDH1A1CTNNB1MMEACECPA1 | |
| SCHEMBL9554924 | 0.84 | MME (0.48) | ALDH1A1CTNNB1MMEACECPA1 | |
| SCHEMBL9554930 | 0.84 | MME (0.48) | ALDH1A1CTNNB1MMEACECPA1 | |
| SCHEMBL7296613 | 0.83 | CTNNB1 (0.52) | ALDH1A1CTNNB1MMEACECPA1 | |
| SCHEMBL9740320 | 0.83 | CTSS (0.51) | ALDH1A1CTNNB1MMEACECPA1 | |
| SCHEMBL7429100 | 0.82 | CPA1 (0.57) | CTNNB1MMEACECPA1ACE2 | |
| SCHEMBL10338654 | 0.82 | CPA1 (0.57) | CTNNB1MMEACECPA1ACE2 | |
| SCHEMBL9194477 | 0.82 | CPA1 (0.57) | CTNNB1MMEACECPA1ACE2 | |
| SCHEMBL6677809 | 0.81 | CTNNB1 (0.63) | CTNNB1MMEACECPA1ACE2 | |
| SCHEMBL10390101 | 0.81 | SLC15A1 (0.55) | ALDH1A1CTNNB1MMEACECPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4857650-A | Novel renin inhibitory amino acid derivatives | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1989-08-15 | — | — | US | disclosed |
| EP-0206807-A2 | Novel amino acid derivatives | Kissei Pharmaceutical Co. Ltd. (JP) | 1986-12-30 | — | — | EP | disclosed |