Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | FPR3 | P25089 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10592068 | 0.98 | MAOB (0.40) | KDM4EADRB2MEN1TP53CYP3A4 | |
| SCHEMBL10077369 | 0.85 | CDK1 (0.42) | KDM4EADRB2MEN1TP53CYP3A4 | |
| SCHEMBL10461865 | 0.83 | ADRB2 (0.39) | KDM4EADRB2MEN1TP53CYP3A4 | |
| SCHEMBL10076826 | 0.83 | MAOB (0.43) | MEN1KMT2AMAOBLMNA | |
| SCHEMBL9762754 | 0.83 | LIMK2 (0.44) | KDM4EADRB2MEN1TP53CYP3A4 | |
| SCHEMBL9763759 | 0.83 | ADRB2 (0.41) | KDM4EADRB2MEN1TP53CYP3A4 | |
| SCHEMBL9763473 | 0.81 | ADRB2 (0.41) | KDM4EADRB2MEN1TP53CYP3A4 | |
| Hydrochloric Acid SCHEMBL11671409 | 0.81 | PKM (0.43) | MAOBBCHEACHE | |
| SCHEMBL10460539 | 0.81 | MAOB (0.38) | KDM4EADRB2MEN1TP53CYP3A4 | |
| SCHEMBL9574173 | 0.81 | MAOB (0.43) | MEN1KMT2AMAOBBCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4853381-A | Ethanolamine compounds | GLAXO GROUP LIMITED (GB) | 1989-08-01 | — | — | US | disclosed |
| EP-0162576-B1 | ETHANOLAMINE COMPOUNDS | GLAXO GROUP LIMITED (GB) | 1989-07-26 | — | — | EP | disclosed |
| EP-0162576-A1 | Ethanolamine compounds | GLAXO GROUP LIMITED (GB) | 1985-11-27 | — | — | EP | disclosed |