Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 5/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | FPR3 | P25089 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10460539 | 0.98 | MAOB (0.38) | ADRB2ADRB1ADRB3CYP1A2CYP3A4 | |
| SCHEMBL10461217 | 0.84 | ADRB2 (0.37) | ADRB2ADRB1ADRB3CYP1A2CYP3A4 | |
| SCHEMBL10477860 | 0.83 | KDM4E (0.41) | ADRB2ADRB1ADRB3CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL11671409 | 0.82 | PKM (0.43) | MAOBHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL10592068 | 0.81 | MAOB (0.40) | ADRB2ADRB1ADRB3CYP1A2CYP3A4 | |
| SCHEMBL9762641 | 0.79 | CCR5 (0.41) | ADRB2ADRB1ADRB3CYP1A2CYP3A4 | |
| SCHEMBL9762777 | 0.79 | ALDH1A1 (0.45) | ADRB2ADRB1ADRB3CYP1A2CYP3A4 | |
| SCHEMBL9763673 | 0.79 | ADRB2 (0.40) | ADRB2ADRB1ADRB3CYP1A2CYP3A4 | |
| SCHEMBL9763053 | 0.79 | ADRB2 (0.41) | ADRB2ADRB1ADRB3CYP1A2CYP3A4 | |
| SCHEMBL9762754 | 0.79 | LIMK2 (0.44) | ADRB2ADRB1ADRB3CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4963564-A | ADRENERGIC STIMULANTS | GLAXO GROUP LTD. (GB) | 1990-10-16 | — | — | US | disclosed |
| EP-0303465-A2 | Phenethanolamine derivatives | GLAXO GROUP LIMITED (GB) | 1989-02-15 | — | — | EP | disclosed |