Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 3/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | EP300 | Q09472 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3448202 | 0.95 | ESR1 (0.34) | PGRESR1CHRM2ADORA3AR | |
| SCHEMBL7531500 | 0.85 | PGR (0.42) | PGRESR1CHRM2ADORA3AR | |
| SCHEMBL9648799 | 0.80 | ESR1 (0.38) | PGRESR1CHRM2ADORA3AR | |
| SCHEMBL18489316 | 0.79 | ESR1 (0.35) | PGRESR1CHRM2ADORA3AR | |
| SCHEMBL29288035 | 0.74 | PGR (0.40) | PGRESR1CHRM2ADORA3AR | |
| SCHEMBL9345533 | 0.73 | LMNA (0.35) | PGRESR1CHRM2ADORA3AR | |
| SCHEMBL7775453 | 0.72 | ESR1 (0.35) | PGRESR1CHRM2ADORA3AR | |
| SCHEMBL27578460 | 0.71 | — | — | |
| SCHEMBL6218005 | 0.70 | — | — | |
| SCHEMBL9006813 | 0.70 | SLC6A3 (0.36) | PGRESR1CHRM2ADORA3AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4855316-A | NONHABIT-FORMING | WARNER-LAMBERT COMPANY (US) | 1989-08-08 | — | — | US | disclosed |