Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4065474 | 0.85 | ADRB1 (0.53) | ADRB1ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL11067105 | 0.80 | ADRB1 (0.74) | ADRB1ALDH1A1NPSR1TSHRMAPK1 | |
| SCHEMBL11504386 | 0.80 | ADRB1 (0.62) | ADRB1ALDH1A1NPSR1TSHRMAPK1 | |
| SCHEMBL23843550 | 0.76 | ADRB1 (0.69) | ADRB1ALDH1A1NPSR1TSHRMAPK1 | |
| SCHEMBL29058159 | 0.76 | ADRB1 (0.69) | ADRB1ALDH1A1NPSR1TSHRMAPK1 | |
| SCHEMBL9065218 | 0.75 | LMNA (0.68) | ADRB1ALDH1A1NPSR1TSHRMAPK1 | |
| SCHEMBL8894088 | 0.75 | LMNA (0.68) | ADRB1ALDH1A1NPSR1TSHRMAPK1 | |
| SCHEMBL30228454 | 0.75 | LMNA (0.68) | ADRB1ALDH1A1NPSR1TSHRMAPK1 | |
| SCHEMBL4072207 | 0.74 | ADRB1 (0.50) | ADRB1ALDH1A1NPSR1TSHRMAPK1 | |
| SCHEMBL13243993 | 0.73 | ADRB1 (0.65) | ADRB1ALDH1A1NPSR1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4855316-A | NONHABIT-FORMING | WARNER-LAMBERT COMPANY (US) | 1989-08-08 | — | — | US | disclosed |