Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | AGXT | P21549 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2396386 | 0.80 | LOXL2 (0.46) | LMNASMN1; SMN2L3MBTL1LOXL2ALDH1A1 | |
| SCHEMBL2393157 | 0.80 | LOXL2 (0.53) | LOXL2ALDH1A1HPGDESR1ESR2 | |
| SCHEMBL7030964 | 0.70 | MAOB (0.50) | LMNALOXL2ALDH1A1KDM4EAGXT | |
| SCHEMBL6013090 | 0.70 | LOXL2 (0.60) | LMNASMN1; SMN2L3MBTL1LOXL2AGXT | |
| SCHEMBL2327568 | 0.70 | LMNA (0.66) | LMNASMN1; SMN2L3MBTL1ALDH1A1HPGD | |
| SCHEMBL11101351 | 0.70 | ESR1 (0.54) | LMNASMN1; SMN2LOXL2ALDH1A1ESR1 | |
| SCHEMBL5947962 | 0.70 | MAOB (0.52) | SMN1; SMN2LOXL2ALDH1A1HPGDESR1 | |
| SCHEMBL31499129 | 0.69 | LOXL2 (0.64) | SMN1; SMN2L3MBTL1LOXL2ESR1ESR2 | |
| SCHEMBL515109 | 0.69 | LOXL2 (0.64) | SMN1; SMN2L3MBTL1LOXL2ESR1ESR2 | |
| SCHEMBL21366386 | 0.69 | ALDH1A1 (0.49) | SMN1; SMN2L3MBTL1LOXL2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4822809-A | ENZYME INHIBITORS | ABBOTT LABORATORIES (US) | 1989-04-18 | — | — | US | disclosed |