Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 6/20 | 0.62 |
| ▸ | HTR2A | P28223 | 4/20 | 0.62 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.62 |
| ▸ | DRD3 | P35462 | 4/20 | 0.62 |
| ▸ | DRD2 | P14416 | 3/20 | 0.62 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.62 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.62 |
| ▸ | HTR2C | P28335 | 3/20 | 0.62 |
| ▸ | HRH1 | P35367 | 3/20 | 0.62 |
| ▸ | HTR2B | P41595 | 3/20 | 0.62 |
| ▸ | DRD1 | P21728 | 3/20 | 0.62 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.62 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.62 |
| ▸ | HTR6 | P50406 | 2/20 | 0.62 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.62 |
| ▸ | LMNA | P02545 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10480879 | 0.90 | KDM1A (0.59) | CYP2D6HTR2AADRA2ASLC6A2SLC6A4 | |
| SCHEMBL10480880 | 0.88 | DRD3 (0.65) | CYP2D6HTR2AADRA2ASLC6A2SLC6A4 | |
| SCHEMBL10481071 | 0.87 | KDM1A (0.54) | CYP2D6HTR2AADRA2ASLC6A2SLC6A4 | |
| SCHEMBL10480885 | 0.83 | KDM1A (0.64) | CYP2D6HTR2AADRA2ASLC6A2SLC6A4 | |
| SCHEMBL11743885 | 0.82 | DRD2 (0.73) | CYP2D6HTR2AADRA2ASLC6A2SLC6A4 | |
| Fumaric Acid SCHEMBL10481039 | 0.81 | LMNA (0.53) | CYP2D6HTR2AADRA2ASLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL11749117 | 0.80 | DRD2 (0.71) | CYP2D6HTR2AADRA2ASLC6A2SLC6A4 | |
| SCHEMBL10480876 | 0.80 | HRH1 (0.61) | HTR2AADRA2ASLC6A2SLC6A4DRD3 | |
| SCHEMBL11686337 | 0.79 | LMNA (0.67) | CYP2D6HTR2AADRA2ASLC6A2SLC6A4 | |
| SCHEMBL10480976 | 0.78 | FPR2 (0.61) | CYP2D6HTR2AADRA2ASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4822796-A | ANALGESIC, PSYCHOLOGICAL DISORDERS | AVENTIS HOLDINGS INC. | 1989-04-18 | — | — | US | disclosed |