Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.36 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.36 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10481983 | 0.89 | HRH4 (0.41) | MAPTPOLBSMN1; SMN2L3MBTL1BCHE | |
| SCHEMBL10481993 | 0.86 | MAPT (0.45) | MEN1KMT2AMAPTPOLBSMN1; SMN2 | |
| SCHEMBL10481974 | 0.84 | ACHE (0.41) | MEN1KMT2AMAPTPOLBSMN1; SMN2 | |
| SCHEMBL10482101 | 0.84 | MAPT (0.46) | MEN1KMT2AMAPTPOLBSMN1; SMN2 | |
| SCHEMBL10481927 | 0.76 | ACHE (0.47) | MAPTPOLBSMN1; SMN2NPSR1CYP1A2 | |
| SCHEMBL10481950 | 0.75 | METAP1 (0.51) | MEN1KMT2AMAPTPOLBSMN1; SMN2 | |
| SCHEMBL6919274 | 0.73 | MEN1 (0.48) | MEN1KMT2AMAPTCYP1A2CYP2D6 | |
| SCHEMBL10482089 | 0.73 | MAPT (0.44) | MAPTSMN1; SMN2BCHEACHEALDH1A1 | |
| SCHEMBL15131972 | 0.72 | KMT2A (0.57) | MEN1KMT2AMAPTNPSR1KDM4E | |
| SCHEMBL10608330 | 0.72 | GPR39 (0.41) | KMT2ABCHEACHECHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4808612-A | ANTIINFLAMMATORY AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-02-28 | — | — | US | claimed |
| US-4808612-A | ANTIINFLAMMATORY AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-02-28 | — | — | US | disclosed |