Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 4/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | MAT2A | P31153 | 1/20 | 0.41 |
| ▸ | TACR3 | P29371 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.40 |
| ▸ | P2RX2 | Q9UBL9 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10481993 | 0.82 | MAPT (0.45) | MAPTSMN1; SMN2LMNAACHEBCHE | |
| SCHEMBL10575185 | 0.80 | ACHE (0.49) | MAPTSMN1; SMN2ALDH1A1ACHEBCHE | |
| SCHEMBL10611520 | 0.79 | ACHE (0.44) | MAPTSMN1; SMN2NPC1RAB9AACHE | |
| SCHEMBL10608330 | 0.79 | GPR39 (0.41) | ACHEBCHECHRM1EPHX2P2RX3 | |
| SCHEMBL10608343 | 0.78 | KMT2A (0.45) | MAPTSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL10481965 | 0.76 | MAPT (0.53) | MAPTSMN1; SMN2LMNAACHEBCHE | |
| SCHEMBL10481983 | 0.76 | HRH4 (0.41) | MAPTSMN1; SMN2ACHEBCHETP53 | |
| SCHEMBL10481923 | 0.73 | MAPT (0.45) | MAPTSMN1; SMN2LMNAACHEBCHE | |
| SCHEMBL10610084 | 0.73 | SMN1; SMN2 (0.41) | MAPTSMN1; SMN2ALDH1A1NPC1HPGD | |
| SCHEMBL10481998 | 0.73 | MEN1 (0.40) | MAPTSMN1; SMN2ALDH1A1ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4808612-A | ANTIINFLAMMATORY AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-02-28 | — | — | US | disclosed |