SCHEMBL1048205

SCHEMBL1048205

COc1ccc(C=Cc2nc(C(Br)(Br)Br)nc(C(Br)(Br)Br)n2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.51
KDM4E B2RXH2 3/20 0.51
CYP3A4 P08684 2/20 0.51
NPC1 O15118 1/20 0.51
CYP2D6 P10635 1/20 0.51
CYP2C9 P11712 1/20 0.51
HPGD P15428 1/20 0.51
CYP2C19 P33261 1/20 0.51
RAB9A P51151 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
RELA Q04206 2/20 0.50
TRPA1 O75762 1/20 0.50
CYP1A1 P04798 3/20 0.49
CYP1B1 Q16678 3/20 0.49
ESR1 P03372 2/20 0.49
MAPT P10636 2/20 0.49
PTGS2 P35354 2/20 0.49
TUBB4A P04350 2/20 0.49
TUBB P07437 2/20 0.49
TUBA3C P0DPH7 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1048204 1.00 CYP1A2 (0.51) CYP1A2KDM4ECYP3A4NPC1CYP2D6
SCHEMBL8852597 0.91 MAPT (0.56) CYP1A2KDM4ECYP3A4NPC1CYP2D6
SCHEMBL51497 0.85 CYP1A2 (0.50) CYP1A2KDM4ECYP3A4NPC1CYP2D6
SCHEMBL51498 0.85 CYP1A2 (0.50) CYP1A2KDM4ECYP3A4NPC1CYP2D6
SCHEMBL21940412 0.85 CYP1A2 (0.50) CYP1A2KDM4ECYP3A4NPC1CYP2D6
Hydrogen Sulfide SCHEMBL30503988 0.84 CYP1A2 (0.49) CYP1A2KDM4ECYP3A4NPC1CYP2D6
SCHEMBL24897242 0.84 CYP1A2 (0.64) CYP1A2KDM4ECYP3A4NPC1CYP2D6
SCHEMBL7803315 0.83 TUBB4A (0.60) CYP1A2CYP1A1CYP1B1TUBB4ATUBB
SCHEMBL7803314 0.83 TUBB4A (0.60) CYP1A2CYP1A1CYP1B1TUBB4ATUBB
SCHEMBL7160271 0.78 ADORA3 (0.48) CYP1A2KDM4ECYP3A4NPC1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0621508-B1 Radiation sensitive resin composition JAPAN SYNTHETIC RUBBER CO LTD (JP) 1996-09-25 EP claimed
US-5494777-A Radiation sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1996-02-27 US claimed
EP-0621508-A1 Radiation sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1994-10-26 EP claimed
US-11746255-B2 Hard-mask composition IRRESISTIBLE MATERIALS LTD (GB) 2023-09-05 US disclosed
CN-109562944-B Hard mask composition 亚历克斯·菲利普·格雷厄姆·罗宾逊 2022-09-09 CN disclosed
CN-112119133-B Hard mask composition 亚历克斯·P·G·罗宾逊 2022-05-24 CN disclosed
US-10438808-B2 Hard-mask composition IRRESISTIBLE MATERIALS, LTD (GB) 2019-10-08 US disclosed
US-10290500-B2 Spin on hard mask material IRRESISTIBLE MATERIALS LTD (GB) 2019-05-14 US disclosed
US-20190127604-A1 HARD-MASK COMPOSITION NANO-C, INC. 2019-05-02 US disclosed
WO-2017205272-A1 HARD-MASK COMPOSITION R0BINSON ALEX PHILIP GRAHAM (GB) 2017-11-30 WO disclosed
US-20170345669-A1 HARD-MASK COMPOSITION NANO-C, INC. 2017-11-30 US disclosed
EP-0621509-B1 Use of a radiation sensitive composition in the production of a liquid crystal display device JAPAN SYNTHETIC RUBBER CO LTD (JP) 1998-01-28 EP disclosed
US-5631307-A SULFONIUM ORGANOBORON COMPLEX OR OXOSULFONIUM ORGANOBORON COMPLEX WITH SENSITIZERS TOYO INK MANUFACTURING CO., LTD. (JP) 1997-05-20 US disclosed
US-5609988-A NEGATIVE RESIST, NOVOLAK, METHYLOL OR METHOXYMETHYL CURING AGENT, 2-BENZODIOXOLYL-4,6-BIS(TRICHLOROMETHYL)TRIAZINE ACID GENERATING AGENT JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1997-03-11 US disclosed
EP-0621508-B1 Radiation sensitive resin composition JAPAN SYNTHETIC RUBBER CO LTD (JP) 1996-09-25 EP disclosed
US-5494777-A Radiation sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1996-02-27 US disclosed
EP-0690074-A1 Photopolymerization initiator composition and photopolymerizable composition TOYO INK MANUFACTURING CO., LTD. (JP) 1996-01-03 EP disclosed
EP-0621508-A1 Radiation sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1994-10-26 EP disclosed
EP-0621509-A1 Radiation sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1994-10-26 EP disclosed
EP-0458325-A1 Negative photosensitive composition and method for forming a resist pattern Mitsubishi Chemical Corporation (JP) 1991-11-27 EP disclosed