Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 3/20 | 0.31 |
| ▸ | CES2 | O00748 | 2/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28115278 | 0.80 | POLB (0.50) | POLBALDH1A1SMN1; SMN2TDP1APEX1 | |
| SCHEMBL30621719 | 0.79 | FAAH (0.39) | POLBALDH1A1SMN1; SMN2TDP1FAAH | |
| SCHEMBL13901852 | 0.77 | APEX1 (0.46) | POLBALDH1A1TDP1APEX1 | |
| SCHEMBL9490818 | 0.77 | CA2 (0.30) | — | |
| SCHEMBL874213 | 0.76 | POLB (0.63) | POLBAPEX1 | |
| SCHEMBL10983897 | 0.75 | CES1 (0.50) | POLBALDH1A1SMN1; SMN2TDP1FAAH | |
| SCHEMBL10773262 | 0.75 | — | — | |
| SCHEMBL14311865 | 0.74 | ALDH1A1 (0.33) | POLBALDH1A1TDP1APEX1 | |
| SCHEMBL10982923 | 0.73 | FAAH (0.37) | POLBALDH1A1SMN1; SMN2FAAHCES2 | |
| SCHEMBL10986415 | 0.73 | PAOX (0.33) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0302441-A2 | Bis-styryl compounds | BASF Aktiengesellschaft (DE) | 1989-02-08 | — | — | EP | disclosed |