SCHEMBL1048414

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21820782	0.84	METAP2 (0.48)	ALDH1A1TDP1EGFRMETAP2CYP3A4
	SCHEMBL29776924	0.84	METAP2 (0.48)	ALDH1A1TDP1EGFRMETAP2CYP3A4
	SCHEMBL12440897	0.83	ALDH1A1 (0.46)	ALDH1A1TDP1ACHEMCL1CYP3A4
	SCHEMBL12440901	0.80	APEX1 (0.60)	ALDH1A1TDP1ACHEMCL1NPC1
	SCHEMBL12128093	0.80	ALDH1A1 (0.43)	ALDH1A1TDP1ACHEMCL1TSHR
	SCHEMBL23182450	0.79	AKR1C2 (0.43)	ALDH1A1TDP1MCL1CYP3A4TSHR
	SCHEMBL2741575	0.79	KIF11 (0.46)	ALDH1A1TDP1ACHEMCL1AR
	SCHEMBL18830634	0.79	NPC1 (0.40)	ALDH1A1TDP1ACHEMCL1CYP3A4
	SCHEMBL171890	0.78	—	—
	SCHEMBL29471000	0.78	—	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.