Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 3/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | IDE | P14735 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | CASR | P41180 | 2/20 | 0.36 |
| ▸ | MLNR | O43193 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL9517956 | 0.73 | SLC6A2 (0.45) | SLC2A1NQO2MEN1KMT2AAPAF1 | |
| Sulfuric Acid SCHEMBL9517959 | 0.73 | SLC6A2 (0.45) | SLC2A1NQO2MEN1KMT2AAPAF1 | |
| SCHEMBL10484353 | 0.71 | MTNR1A (0.45) | NQO2KMT2AMTNR1AMCL1SIGMAR1 | |
| Sulfuric Acid SCHEMBL9517964 | 0.71 | HTR7 (0.41) | SLC2A1NQO2SLC6A2SLC6A4ADRA2C | |
| SCHEMBL10484195 | 0.69 | L3MBTL1 (0.32) | MEN1KMT2AMTNR1AP2RX1P2RX3 | |
| SCHEMBL10484232 | 0.68 | MTNR1A (0.42) | KMT2AMTNR1AMCL1SIGMAR1 | |
| Sulfuric Acid SCHEMBL10484343 | 0.67 | CNR2 (0.43) | MEN1KMT2ASLC6A2SLC6A4ADRA2C | |
| SCHEMBL12039318 | 0.65 | NQO2 (0.49) | NQO2MTNR1AMCL1TRPV1 | |
| SCHEMBL3804054 | 0.65 | MTNR1A (0.42) | NQO2MEN1KMT2AAPAF1IDE | |
| SCHEMBL10484191 | 0.65 | ACP3 (0.43) | NQO2MEN1KMT2AMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4876282-A | ANTIDEPRESSANT, DIETETICS, ANTIALCOHOLISM AGENT | ELI LILLY AND COMPANY (US) | 1989-10-24 | — | — | US | disclosed |
| EP-0318234-A2 | Improvements in or relating to selective serotonin uptake inhibitors | ELI LILLY AND COMPANY (US) | 1989-05-31 | — | — | EP | disclosed |