Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 10/20 | 0.32 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5698928 | 0.84 | FDPS (0.33) | FDPS | |
| SCHEMBL28250479 | 0.82 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2FDPSGGPS1LMNA | |
| SCHEMBL2846775 | 0.81 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2FDPSGGPS1LMNA | |
| SCHEMBL27613447 | 0.79 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2FDPSGGPS1LMNA | |
| SCHEMBL28642670 | 0.76 | ESR1 (0.38) | ALDH1A1FDPSGGPS1LMNATSHR | |
| SCHEMBL29445835 | 0.75 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2FDPSGGPS1LMNA | |
| SCHEMBL8817467 | 0.75 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL8817966 | 0.75 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL28644619 | 0.74 | FDPS (0.34) | ALDH1A1SMN1; SMN2FDPSGGPS1LMNA | |
| SCHEMBL8864003 | 0.73 | FDPS (0.37) | ALDH1A1FDPSGGPS1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4861813-A | 5-Aralkyl substituted 2h-benzotriazoles in stabilized compositions | CIBA-GEIGY CORPORATION (US) | 1989-08-29 | — | — | US | disclosed |