SCHEMBL2846775

SCHEMBL2846775

CCCCC(CO)(CO)C(CO)(CCCC)CCCC

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.38
TSHR P16473 4/20 0.36
LMNA P02545 3/20 0.36
HSD17B10 Q99714 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
FDPS P14324 2/20 0.36
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33
THRB P10828 1/20 0.32
TNNC1 P63316 5/20 0.31
SGPL1 O95470 1/20 0.31
S1PR4 O95977 1/20 0.31
S1PR1 P21453 1/20 0.31
GPR183 P32249 1/20 0.31
CERS2 Q96G23 1/20 0.31
S1PR3 Q99500 1/20 0.31
S1PR5 Q9H228 1/20 0.31
GGPS1 O95749 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2854867 0.89 LMNA (0.46) ALDH1A1SMN1; SMN2TSHRLMNAHSD17B10
SCHEMBL2848772 0.89 LMNA (0.46) ALDH1A1SMN1; SMN2TSHRLMNAHSD17B10
SCHEMBL2852624 0.89 LMNA (0.46) ALDH1A1SMN1; SMN2TSHRLMNAHSD17B10
SCHEMBL28250479 0.83 ALDH1A1 (0.36) ALDH1A1SMN1; SMN2TSHRLMNAHSD17B10
SCHEMBL10484351 0.81 ALDH1A1 (0.35) ALDH1A1SMN1; SMN2TSHRLMNAHSD17B10
SCHEMBL27613447 0.80 ALDH1A1 (0.38) ALDH1A1SMN1; SMN2TSHRLMNAHSD17B10
SCHEMBL28416994 0.78 ALDH1A1 (0.36) ALDH1A1SMN1; SMN2TSHRLMNAHSD17B10
SCHEMBL18664523 0.78 CES2 (0.32) ALDH1A1SMN1; SMN2HSD17B10MEN1KMT2A
SCHEMBL18638258 0.78 CES2 (0.32) ALDH1A1SMN1; SMN2HSD17B10MEN1KMT2A
SCHEMBL29445835 0.76 ALDH1A1 (0.35) ALDH1A1SMN1; SMN2TSHRLMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2159274-B1 BRAKE FLUID CONTAINING TETRAZOLE CHIYODA CHEMICAL CO LTD (JP) 2013-04-17 EP disclosed
US-8357642-B2 Functional fluid CHIYODA CHEMICAL CO., LTD. (JP) 2013-01-22 US disclosed
US-20100137174-A1 FUNCTIONAL FLUID CHIYODA CHEMICAL CO., LTD. (JP) 2010-06-03 US disclosed
EP-2159274-A1 FUNCTIONAL FLUID Chiyoda Chemical Co. Ltd (JP) 2010-03-03 EP disclosed