Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | HTR7 | P34969 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10485693 | 0.90 | HTR7 (0.63) | MAPTHTR7ABCB1SMN1; SMN2MAPK1 | |
| Hydrochloric Acid SCHEMBL10485667 | 0.89 | HTR7 (0.62) | MAPTHTR7ABCB1SMN1; SMN2MAPK1 | |
| SCHEMBL10485560 | 0.87 | HTR7 (0.72) | MAPTHTR7ABCB1TDP1ADRB2 | |
| SCHEMBL10485984 | 0.86 | HTR7 (0.58) | MAPTHTR7ALDH1A1ABCB1SMN1; SMN2 | |
| SCHEMBL10901035 | 0.85 | ALDH1A1 (0.58) | MAPTALDH1A1TSHR | |
| SCHEMBL10485585 | 0.85 | MAPT (0.70) | MAPTHTR7ALDH1A1TSHRTDP1 | |
| SCHEMBL10485995 | 0.84 | HTR7 (0.56) | MAPTHTR7ALDH1A1ABCB1SMN1; SMN2 | |
| SCHEMBL10485545 | 0.83 | MAPT (0.63) | MAPTHTR7ALDH1A1TSHRTDP1 | |
| SCHEMBL10485596 | 0.83 | HTR7 (0.80) | MAPTHTR7ALDH1A1ABCB1MAPK1 | |
| Hydrochloric Acid SCHEMBL10485689 | 0.82 | HTR7 (0.78) | MAPTHTR7ALDH1A1ABCB1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4882330-A | 1-aryloxy-4-[((4-aryl)-1-piperazinyl]-2-butanols useful as antiallergy agents | A. H. ROBINS COMPANY, INCORPORATED (US) | 1989-11-21 | — | — | US | disclosed |
| EP-0269383-A2 | 1-Aryloxy-4-[(4-aryl)-1-piperazinyl]-2-butanols useful as antiallergy agents | A.H. ROBINS COMPANY, INCORPORATED (US) | 1988-06-01 | — | — | EP | disclosed |