Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.58 |
| ▸ | THRA | P10827 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 3/20 | 0.55 |
| ▸ | DRD3 | P35462 | 3/20 | 0.55 |
| ▸ | HTR1A | P08908 | 2/20 | 0.55 |
| ▸ | HTR2A | P28223 | 2/20 | 0.55 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.55 |
| ▸ | HRH1 | P35367 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | HRH2 | P25021 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10897498 | 0.86 | KCNH2 (0.61) | KCNA5HRH3KCNH2DRD2DRD3 | |
| SCHEMBL10900979 | 0.85 | DRD2 (0.63) | KCNA5THRATHRBHRH3DRD2 | |
| SCHEMBL10486108 | 0.85 | MAPT (0.56) | ALDH1A1TSHRMAPT | |
| SCHEMBL8205972 | 0.82 | ALDH1A1 (0.58) | ALDH1A1TSHRKCNH2DRD2SIGMAR1 | |
| SCHEMBL10902040 | 0.82 | KCNJ1 (0.57) | ALDH1A1TSHRKCNH2DRD2HTR1A | |
| SCHEMBL10897483 | 0.82 | HRH3 (0.55) | ALDH1A1TSHRHRH3KCNH2DRD2 | |
| SCHEMBL10899514 | 0.81 | SIGMAR1 (0.61) | ALDH1A1TSHRKCNH2HTR2ASIGMAR1 | |
| SCHEMBL21408538 | 0.81 | HRH3 (0.79) | ALDH1A1TSHRTHRBHRH3KCNH2 | |
| SCHEMBL22015905 | 0.81 | HPGD (0.65) | ALDH1A1TSHRMEN1KMT2AMAPT | |
| SCHEMBL20188098 | 0.81 | HPGD (0.65) | ALDH1A1TSHRMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4616086-A | ANTICOAGULANTS | BOEHRINGER MANNHEIM GMBH (DE) | 1986-10-07 | — | — | US | disclosed |