Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.40 |
| ▸ | CXCR1 | P25024 | 3/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9546062 | 0.87 | FFAR1 (0.47) | FAAHPTGS1PTGS2CXCR1CXCR2 | |
| SCHEMBL10485950 | 0.86 | FFAR1 (0.46) | FAAHPTGS1PTGS2CXCR1CXCR2 | |
| SCHEMBL9546047 | 0.79 | POLB (0.44) | FAAHPTGS1PTGS2ALOX5LMNA | |
| SCHEMBL10486263 | 0.79 | GRIN2D (0.42) | FAAHPTGS1PTGS2CXCR1CXCR2 | |
| SCHEMBL10485947 | 0.78 | OPRK1 (0.40) | PTGS1PTGS2CXCR1CXCR2ALOX5 | |
| SCHEMBL10527841 | 0.78 | ESR1 (0.39) | FAAHPTGS1PTGS2CXCR1CXCR2 | |
| SCHEMBL10527007 | 0.77 | EPHX1 (0.35) | FAAHPTGS1PTGS2CXCR1CXCR2 | |
| SCHEMBL10485777 | 0.76 | OPRM1 (0.43) | PTGS1PTGS2CHRM1PDE4A | |
| SCHEMBL10485707 | 0.75 | OPRK1 (0.40) | PTGS1PTGS2CXCR1CXCR2ALOX5 | |
| SCHEMBL10602088 | 0.74 | FFAR1 (0.46) | LMNABLMACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4883916-A | ANTICHOLESTEROL, ANTIARTERIOSCELEROSIS | EISAI CO., LTD. (JP) | 1989-11-28 | — | — | US | disclosed |
| US-4788330-A | Polyprenyl compounds | EISAI CO., LTD. (JP) | 1988-11-29 | — | — | US | disclosed |