Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10603712 | 0.89 | POLB (0.49) | POLBALDH1A1HPGDOPRK1OPRM1 | |
| SCHEMBL10485777 | 0.85 | OPRM1 (0.43) | POLBALDH1A1HPGDOPRK1OPRM1 | |
| SCHEMBL10485947 | 0.84 | OPRK1 (0.40) | POLBALDH1A1HPGDOPRK1OPRM1 | |
| SCHEMBL10485707 | 0.81 | OPRK1 (0.40) | POLBALDH1A1HPGDOPRK1OPRM1 | |
| SCHEMBL9546062 | 0.80 | FFAR1 (0.47) | TSHRLMNAFAAHCHRM1PDE4A | |
| SCHEMBL10604919 | 0.80 | SMN1; SMN2 (0.48) | POLBALDH1A1HPGDRAB9ACYP3A4 | |
| SCHEMBL10485950 | 0.79 | FFAR1 (0.46) | TSHRLMNAFAAHCHRM1PDE4A | |
| SCHEMBL10486233 | 0.79 | FAAH (0.40) | TSHRLMNAFAAHCHRM1PDE4A | |
| SCHEMBL10605338 | 0.79 | SMN1; SMN2 (0.47) | POLBALDH1A1HPGDRAB9ACYP3A4 | |
| SCHEMBL10606790 | 0.79 | SMN1; SMN2 (0.47) | POLBALDH1A1HPGDRAB9ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337350-B1 | USE OF DIMETHYLHEPTYLPHENYL BUTANOYL ETHANOLAMINE IN TREATMENT OF HYPERURICEMIA | Eisai Co., Ltd. (JP) | 1993-07-07 | — | — | EP | claimed |
| US-4883821-A | N-(3-(4'-(2\",6\"-DIMETHYLHEPTYL)PHENYL)BUTANOYL)-ETHANOLAMINE | EISAI CO., LTD. (JP) | 1989-11-28 | — | — | US | claimed |
| EP-0337350-A2 | Use of dimethylheptylphenyl butanoyl ethanolamine in treatment of hyperuricemia | Eisai Co., Ltd. (JP) | 1989-10-18 | — | — | EP | claimed |
| EP-0194693-B1 | POLYPRENYL COMPOUNDS, PROCESSES FOR PREPARING THEM, AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | Eisai Co., Ltd. (JP) | 1989-07-26 | — | — | EP | claimed |
| JP-2028113-A | — | — | None | — | — | JP | disclosed |
| EP-0337350-B1 | USE OF DIMETHYLHEPTYLPHENYL BUTANOYL ETHANOLAMINE IN TREATMENT OF HYPERURICEMIA | Eisai Co., Ltd. (JP) | 1993-07-07 | — | — | EP | disclosed |
| JP-H0228113-A | IMPROVING AND TREATING AGENT FOR HYPERURICEMIA | EISAI CO LTD | 1990-01-30 | — | — | JP | disclosed |
| US-4883821-A | N-(3-(4'-(2\",6\"-DIMETHYLHEPTYL)PHENYL)BUTANOYL)-ETHANOLAMINE | EISAI CO., LTD. (JP) | 1989-11-28 | — | — | US | disclosed |
| US-4883916-A | ANTICHOLESTEROL, ANTIARTERIOSCELEROSIS | EISAI CO., LTD. (JP) | 1989-11-28 | — | — | US | disclosed |
| EP-0337350-A2 | Use of dimethylheptylphenyl butanoyl ethanolamine in treatment of hyperuricemia | Eisai Co., Ltd. (JP) | 1989-10-18 | — | — | EP | disclosed |
| US-4788330-A | Polyprenyl compounds | EISAI CO., LTD. (JP) | 1988-11-29 | — | — | US | disclosed |