Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 2/20 | 0.43 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.39 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10486277 | 0.84 | MAPK14 (0.45) | MAPK14TAOK1TAOK3SLC6A3RAB9A | |
| SCHEMBL10486405 | 0.84 | SLC6A3 (0.50) | SLC6A3ALDH1A1CHRNB2CHRNA4 | |
| SCHEMBL10486030 | 0.83 | RARG (0.41) | SLC6A3KMT2AKDM4EALDH1A1ALOX15 | |
| SCHEMBL10486068 | 0.72 | SLC6A3 (0.45) | SLC6A3RAB9AALDH1A1CHRNB2CHRNA4 | |
| SCHEMBL10486417 | 0.72 | RXRA (0.42) | SLC6A3KMT2AKDM4EALDH1A1ALOX15 | |
| SCHEMBL14157778 | 0.71 | HPGDS (0.55) | RAB9AKMT2ACYP17A1ALDH1A1HDAC3 | |
| SCHEMBL3949393 | 0.69 | HDAC3 (0.62) | RAB9AKMT2AHDAC3HDAC4HDAC1 | |
| SCHEMBL10486412 | 0.68 | RARG (0.44) | KMT2AKDM4EALDH1A1ALOX15 | |
| SCHEMBL10486065 | 0.68 | SLC6A3 (0.47) | SLC6A3ALDH1A1CHRNB2CHRNA4 | |
| SCHEMBL13861733 | 0.67 | CHRNB2 (0.41) | KDM4EPDK2CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4810694-A | SKIN DISORDERS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (C.I.R.D.) (FR) | 1989-03-07 | — | — | US | disclosed |