Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GHSR | Q92847 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 3/20 | 0.33 |
| ▸ | VEGFA | P15692 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.32 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.32 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.32 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.32 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.32 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.32 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.32 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.32 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.32 |
| ▸ | CACNG1 | Q06432 | 1/20 | 0.32 |
| ▸ | CACNB2 | Q08289 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10486490 | 0.69 | GHSR (0.44) | GHSR | |
| SCHEMBL9157283 | 0.63 | DRD2 (0.46) | ESR2ESR1GPR119MEN1KMT2A | |
| SCHEMBL9163267 | 0.63 | DRD2 (0.46) | ESR2ESR1GPR119MEN1KMT2A | |
| SCHEMBL9156416 | 0.63 | DRD2 (0.40) | ESR2ESR1GPR119LMNADRD2 | |
| SCHEMBL9163915 | 0.63 | DRD2 (0.44) | ESR2ALDH1A1ESR1GPR119MEN1 | |
| SCHEMBL9160117 | 0.63 | DRD2 (0.40) | ESR2ESR1GPR119LMNADRD2 | |
| SCHEMBL9162378 | 0.63 | DRD2 (0.44) | ESR2ALDH1A1ESR1GPR119MEN1 | |
| SCHEMBL9162204 | 0.63 | DRD1 (0.55) | ESR2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL9161077 | 0.63 | DRD1 (0.55) | ESR2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL11912526 | 0.63 | KIF11 (0.56) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4861771-A | Carbamates of 6-chloro-7,8-dihydroxy-1-(4'-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine as prodrugs | SMITHKLINE BECKMAN CORPORATION (US) | 1989-08-29 | — | — | US | disclosed |