Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 9/20 | 0.44 |
| ▸ | YAP1 | P46937 | 3/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9157251 | 0.75 | YAP1 (0.44) | GHSRYAP1PRMT5 | |
| SCHEMBL10486477 | 0.74 | GHSR (0.43) | GHSRYAP1 | |
| SCHEMBL9160083 | 0.73 | YAP1 (0.44) | GHSRYAP1PRMT5 | |
| SCHEMBL9158709 | 0.72 | YAP1 (0.44) | GHSRYAP1PRMT5 | |
| SCHEMBL9162086 | 0.71 | DRD1 (0.52) | YAP1PRMT5 | |
| SCHEMBL3079062 | 0.70 | GHSR (0.67) | GHSR | |
| SCHEMBL10486502 | 0.69 | ESR2 (0.34) | GHSR | |
| SCHEMBL9161002 | 0.69 | YAP1 (0.44) | GHSRYAP1PRMT5 | |
| SCHEMBL3061794 | 0.68 | GHSR (0.65) | GHSR | |
| SCHEMBL3056802 | 0.68 | GHSR (0.65) | GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4861771-A | Carbamates of 6-chloro-7,8-dihydroxy-1-(4'-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine as prodrugs | SMITHKLINE BECKMAN CORPORATION (US) | 1989-08-29 | — | — | US | disclosed |