Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10487314 | 1.00 | THRA (0.41) | THRATHRBLIPGALOX5PTGS2 | |
| SCHEMBL10487305 | 0.84 | THRA (0.43) | THRATHRBLIPGALOX5PTGS2 | |
| SCHEMBL10487302 | 0.82 | THRA (0.37) | THRATHRBALOX5PTGS2CYP3A4 | |
| SCHEMBL5390353 | 0.81 | THRA (0.49) | THRATHRBLIPGALOX5PTGS2 | |
| SCHEMBL10816673 | 0.81 | STS (0.42) | THRATHRBLIPGPTGS2PPARA | |
| SCHEMBL10487316 | 0.81 | STS (0.42) | THRATHRBLIPGPTGS2PPARA | |
| SCHEMBL11252007 | 0.79 | GHSR (0.38) | THRATHRBLIPGALOX5PTGS2 | |
| SCHEMBL6849772 | 0.78 | THRA (0.59) | THRATHRBLIPGALOX5PTGS2 | |
| SCHEMBL1100557 | 0.78 | THRA (0.59) | THRATHRBLIPGALOX5PTGS2 | |
| SCHEMBL8393505 | 0.78 | THRA (0.59) | THRATHRBLIPGALOX5PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4707509-A | Tris-organophosphite compositions having improved hydrolytic stability | ARGUS CHEMICAL CORPORATION (US) | 1987-11-17 | — | — | US | disclosed |
| EP-0167969-A2 | Tris-organophosphite compositions having improved hydrolytic stability | Argus Chemical Corporation (US) | 1986-01-15 | — | — | EP | disclosed |