Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.59 |
| ▸ | CTSS | P25774 | 4/20 | 0.59 |
| ▸ | CTSB | P07858 | 3/20 | 0.59 |
| ▸ | CTSK | P43235 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 2/20 | 0.49 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | ECE1 | P42892 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10487598 | 0.88 | CTSK (0.54) | CTSLCTSSCTSBCTSKCYP3A4 | |
| SCHEMBL10487543 | 0.87 | CTSK (0.55) | CTSLCTSSCTSBCTSKMEN1 | |
| SCHEMBL10969151 | 0.86 | CTSL (0.56) | CTSLCTSSCTSBCTSKCYP3A4 | |
| SCHEMBL10969155 | 0.86 | CTSL (0.56) | CTSLCTSSCTSBCTSKCYP3A4 | |
| SCHEMBL10658290 | 0.80 | CTSK (0.59) | CTSLCTSSCTSBCTSKMEN1 | |
| SCHEMBL10882866 | 0.80 | CTSL (0.53) | CTSLCTSSCTSBCTSKCYP3A4 | |
| SCHEMBL10882861 | 0.80 | CTSL (0.53) | CTSLCTSSCTSBCTSKCYP3A4 | |
| SCHEMBL27310595 | 0.78 | CYP3A4 (0.69) | CTSLCTSSCTSBCTSKCYP3A4 | |
| SCHEMBL24734375 | 0.78 | CTSL (0.71) | CTSLCTSSCTSBCTSKCYP3A4 | |
| SCHEMBL5145628 | 0.78 | CTSL (0.71) | CTSLCTSSCTSBCTSKCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4820729-A | N-substituted-amido-amino acids | RORER PHARMACEUTICAL CORPORATION (US) | 1989-04-11 | — | — | US | disclosed |