Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.56 |
| ▸ | CTSB | P07858 | 3/20 | 0.56 |
| ▸ | CTSS | P25774 | 3/20 | 0.56 |
| ▸ | CTSK | P43235 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10969155 | 1.00 | CTSL (0.56) | CTSLCTSBCTSSCTSKKMT2A | |
| SCHEMBL10882861 | 0.92 | CTSL (0.53) | CTSLCTSBCTSSCTSKKMT2A | |
| SCHEMBL10882866 | 0.92 | CTSL (0.53) | CTSLCTSBCTSSCTSKKMT2A | |
| SCHEMBL10487546 | 0.86 | CTSL (0.59) | CTSLCTSBCTSSCTSKKMT2A | |
| SCHEMBL10658290 | 0.77 | CTSK (0.59) | CTSLCTSBCTSSCTSKKMT2A | |
| SCHEMBL10487598 | 0.76 | CTSK (0.54) | CTSLCTSBCTSSCTSKKMT2A | |
| SCHEMBL24734375 | 0.75 | CTSL (0.71) | CTSLCTSBCTSSCTSKKMT2A | |
| SCHEMBL5145628 | 0.75 | CTSL (0.71) | CTSLCTSBCTSSCTSKKMT2A | |
| SCHEMBL7264750 | 0.75 | CTSL (0.71) | CTSLCTSBCTSSCTSKKMT2A | |
| SCHEMBL8837344 | 0.75 | CTSL (0.71) | CTSLCTSBCTSSCTSKKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4558038-A | HYPOTENSIVE AGENTS | USV PHARMACEUTICAL CORP. (US) | 1985-12-10 | — | — | US | disclosed |
| US-4496542-A | HYPOTENSIVE AGENTS; ENZYME INHIBITORS | USV PHARMACEUTICAL CORPORATION (US) | 1985-01-29 | — | — | US | disclosed |
| EP-0061768-A1 | N-amido substituted dipeptides | USV PHARMACEUTICAL CORPORATION (US) | 1982-10-06 | — | — | EP | disclosed |