Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HCAR3 | P49019 | 11/20 | 0.50 |
| ▸ | TPMT | P51580 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10487699 | 0.89 | TPMT (0.53) | GAAMAPTHCAR3TPMTESR1 | |
| SCHEMBL10606736 | 0.84 | GAA (0.51) | GAAMAPTHCAR3TPMTTSHR | |
| SCHEMBL10608618 | 0.84 | GAA (0.51) | GAAMAPTHCAR3TPMTTSHR | |
| SCHEMBL1515894 | 0.83 | ESR1 (0.59) | GAAMAPTESR1ALDH1A1 | |
| SCHEMBL28503260 | 0.82 | ALDH1A1 (0.58) | MAPTTPMTALDH1A1 | |
| SCHEMBL6180268 | 0.81 | HCAR3 (0.64) | HCAR3TSHRCASP6 | |
| SCHEMBL17399916 | 0.80 | CASP6 (0.60) | HCAR3TSHRCASP6 | |
| SCHEMBL503443 | 0.80 | CASP6 (0.62) | HCAR3TPMTTSHRCASP6ALDH1A1 | |
| SCHEMBL5080677 | 0.80 | GPR35 (0.57) | MAPTTSHRALDH1A1 | |
| SCHEMBL19225449 | 0.80 | GPR35 (0.65) | MAPTESR1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0206635-B1 | PREPARATION OF 3-AMINO-4-HYDROXYBENZOIC ACIDS | THE DOW CHEMICAL COMPANY (US) | 1989-11-15 | — | — | EP | disclosed |
| US-4835306-A | Preparation of 3-amino-4-hydroxybenzoic acids | THE DOW CHEMICAL COMPANY (US) | 1989-05-30 | — | — | US | disclosed |
| EP-0206635-A1 | Preparation of 3-amino-4-hydroxybenzoic acids | THE DOW CHEMICAL COMPANY (US) | 1986-12-30 | — | — | EP | disclosed |