Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 7/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9763650 | 0.86 | MMP12 (0.38) | SLC6A4FAAHALDH1A1 | |
| SCHEMBL9763470 | 0.80 | SLC6A4 (0.38) | SLC6A4ALDH1A1MAOANPC1RAB9A | |
| SCHEMBL9574244 | 0.80 | RAB9A (0.42) | FAAHALDH1A1RAB9A | |
| SCHEMBL9574159 | 0.80 | ALDH1A1 (0.58) | FAAHALDH1A1 | |
| SCHEMBL10477857 | 0.79 | F2RL1 (0.50) | ALDH1A1MAOANPC1RAB9A | |
| SCHEMBL9763063 | 0.78 | HDAC1 (0.50) | ALDH1A1NPC1RAB9A | |
| SCHEMBL9763373 | 0.76 | TSHR (0.46) | ALDH1A1RAB9A | |
| SCHEMBL9574194 | 0.74 | MAPT (0.59) | FAAHALDH1A1 | |
| SCHEMBL9574216 | 0.73 | TDP1 (0.54) | MAOANPC1RAB9A | |
| SCHEMBL9574169 | 0.72 | ALDH1A1 (0.59) | FAAHALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4853382-A | TREATING ASTHMA AND BRONCHITIS | GLAXO GROUP LIMITED (GB) | 1989-08-01 | — | — | US | disclosed |
| EP-0178919-B1 | AMINOPHENOL DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1988-12-21 | — | — | EP | disclosed |
| US-4730008-A | STIMULANT FOR BETA-ADRENORECEPTORS | GLAXO GROUP LIMITED (GB) | 1988-03-08 | — | — | US | disclosed |
| EP-0178919-A2 | Aminophenol derivatives | GLAXO GROUP LIMITED (GB) | 1986-04-23 | — | — | EP | disclosed |